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SLC50A1 Knockout Cell Lines

Gene: SLC50A1

Official Full Name: solute carrier family 50 member 1provided by HGNC

Gene Summary: Enables glucoside transmembrane transporter activity. Predicted to be involved in carbohydrate transport. Located in Golgi apparatus and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO20900 SLC50A1 Knockout cell line (HeLa) Human SLC50A1 1:3~1:6 Negative Online Inquiry
KO20901 SLC50A1 Knockout cell line (HCT 116) Human SLC50A1 1:2~1:4 Negative Online Inquiry
KO20902 SLC50A1 Knockout cell line (HEK293) Human SLC50A1 1:3~1:6 Negative Online Inquiry
KO20903 SLC50A1 Knockout cell line (A549) Human SLC50A1 1:3~1:4 Negative Online Inquiry

Background

SLC50A1 Gene Knockout Cell Lines are genetically modified cell models specifically designed to lack the SLC50A1 gene, which encodes the sodium-dependent organic anion transporter. This product provides researchers with a crucial tool for investigating the physiological and pathological roles of the SLC50A1 transporter in cellular processes. By utilizing these knockout cell lines, scientists can explore the underlying mechanisms of organic anion transport in various tissues, thereby elucidating the gene's involvement in drug uptake, metabolic pathways, and potential disease states.

The key function of the SLC50A1 gene knockout is to enable the study of the impact that the absence of this transporter has on cellular behavior. By employing these cell lines, researchers can conduct experiments to assess changes in cellular metabolism, ion homeostasis, and response to therapeutic agents. This offers insights into how the SLC50A1 transporter interacts with various substrates, which is essential for drug development and the understanding of toxicological effects.

The scientific importance of SLC50A1 gene knockout cell lines extends to numerous applications in both research and clinical settings. They can be utilized to investigate diseases related to altered organic anion transport, such as metabolic disorders, contributing valuable data for potential therapeutic interventions. Moreover, these knockout models facilitate high-throughput screening for drug candidates, improving the efficiency of pharmacological studies.

Compared to alternative models, such as wild-type cells or less specific knockdown methods, SLC50A1 gene knockout cell lines provide a high level of specificity and reproducibility in experimental outcomes. The precision of gene editing ensures that any observed phenotypic changes can be confidently attributed to the loss of the SLC50A1 function, providing an unmatched advantage in dissecting the complexity of biological systems.

For researchers and clinicians looking to enhance their studies in drug metabolism and transport mechanisms, SLC50A1 gene knockout cell lines are invaluable. They offer a unique opportunity to deepen our understanding of cellular transport processes, helping to drive innovative research forward.

As part of our commitment to advancing biological research, our company specializes in providing high-quality genetic models and cell lines tailored for various scientific inquiries. Our expertise ensures that you have access to reliable tools that empower your research and clinical endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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