Gene: SLC39A9
Official Full Name: solute carrier family 39 member 9provided by HGNC
Gene Summary: Enables G protein-coupled receptor activity; androgen binding activity; and zinc efflux transmembrane transporter activity. Involved in intracellular zinc ion homeostasis; regulation of vascular endothelial cell proliferation; and zinc ion transmembrane transport. Located in several cellular components, including mitochondrial membrane; perinuclear region of cytoplasm; and trans-Golgi network. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO20280 | SLC39A9 Knockout cell line (HeLa) | Human | SLC39A9 | 1:3~1:6 | Negative | Online Inquiry |
KO20281 | SLC39A9 Knockout cell line (HCT 116) | Human | SLC39A9 | 1:2~1:4 | Negative | Online Inquiry |
KO20282 | SLC39A9 Knockout cell line (HEK293) | Human | SLC39A9 | 1:3~1:6 | Negative | Online Inquiry |
KO20283 | SLC39A9 Knockout cell line (A549) | Human | SLC39A9 | 1:3~1:4 | Negative | Online Inquiry |
SLC39A9 Gene Knockout Cell Lines are specialized cellular models engineered to lack the SLC39A9 gene, which encodes a member of the ZIP transporter family responsible for the cellular uptake of zinc. This product serves as a powerful tool for studying the physiological and pathological roles of zinc in cellular processes. By completely knocking out the SLC39A9 gene, researchers can investigate the impacts of zinc deficiency on cellular metabolism, growth, and signaling pathways in a controlled environment.
The SLC39A9 gene knockout manifests through a precise and efficient CRISPR-Cas9 genome editing approach, ensuring that the genetic alterations are stable and reproducible. These knockout cell lines allow for in-depth analysis of zinc’s role in critical biological processes, such as oxidative stress response, immune function, and cell signaling. As zinc is an essential trace element linked to various diseases and conditions, these cell lines are particularly valuable for exploring research related to cancer, neurodegenerative diseases, and metabolic disorders.
In comparison to traditional methods of studying zinc dynamics, SLC39A9 Gene Knockout Cell Lines provide a unique advantage by offering researchers a clean model devoid of confounding factors associated with endogenous SLC39A9 expression. This specificity enhances the reliability of results, facilitating the discovery of novel therapeutic targets that can emerge from understanding how zinc influences cell behavior.
Moreover, these cell lines are indispensable in both basic research and potential therapeutic developments, making them a significant resource for academic and clinical laboratories. Given the integral role of zinc in many biological systems, the SLC39A9 Gene Knockout Cell Lines represent a valuable asset for advancing scientific knowledge and potential clinical applications.
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Please note that all services are for research use only. Not intended for any clinical use.
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