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SLC39A9 Knockout Cell Lines

Gene: SLC39A9

Official Full Name: solute carrier family 39 member 9provided by HGNC

Gene Summary: Enables G protein-coupled receptor activity; androgen binding activity; and zinc efflux transmembrane transporter activity. Involved in intracellular zinc ion homeostasis; regulation of vascular endothelial cell proliferation; and zinc ion transmembrane transport. Located in several cellular components, including mitochondrial membrane; perinuclear region of cytoplasm; and trans-Golgi network. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO20280 SLC39A9 Knockout cell line (HeLa) Human SLC39A9 1:3~1:6 Negative Online Inquiry
KO20281 SLC39A9 Knockout cell line (HCT 116) Human SLC39A9 1:2~1:4 Negative Online Inquiry
KO20282 SLC39A9 Knockout cell line (HEK293) Human SLC39A9 1:3~1:6 Negative Online Inquiry
KO20283 SLC39A9 Knockout cell line (A549) Human SLC39A9 1:3~1:4 Negative Online Inquiry

Background

SLC39A9 Gene Knockout Cell Lines are specialized cellular models engineered to lack the SLC39A9 gene, which encodes a member of the ZIP transporter family responsible for the cellular uptake of zinc. This product serves as a powerful tool for studying the physiological and pathological roles of zinc in cellular processes. By completely knocking out the SLC39A9 gene, researchers can investigate the impacts of zinc deficiency on cellular metabolism, growth, and signaling pathways in a controlled environment.

The SLC39A9 gene knockout manifests through a precise and efficient CRISPR-Cas9 genome editing approach, ensuring that the genetic alterations are stable and reproducible. These knockout cell lines allow for in-depth analysis of zinc’s role in critical biological processes, such as oxidative stress response, immune function, and cell signaling. As zinc is an essential trace element linked to various diseases and conditions, these cell lines are particularly valuable for exploring research related to cancer, neurodegenerative diseases, and metabolic disorders.

In comparison to traditional methods of studying zinc dynamics, SLC39A9 Gene Knockout Cell Lines provide a unique advantage by offering researchers a clean model devoid of confounding factors associated with endogenous SLC39A9 expression. This specificity enhances the reliability of results, facilitating the discovery of novel therapeutic targets that can emerge from understanding how zinc influences cell behavior.

Moreover, these cell lines are indispensable in both basic research and potential therapeutic developments, making them a significant resource for academic and clinical laboratories. Given the integral role of zinc in many biological systems, the SLC39A9 Gene Knockout Cell Lines represent a valuable asset for advancing scientific knowledge and potential clinical applications.

Our company prides itself on delivering high-quality biological products backed by rigorous scientific validation, ensuring that our clients have access to reliable tools that drive innovation in research and medicine.

Please note that all services are for research use only. Not intended for any clinical use.

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