Home / SLC39A1 Knockout Cell Lines

SLC39A1 Knockout Cell Lines

Gene: SLC39A1

Official Full Name: solute carrier family 39 member 1provided by HGNC

Gene Summary: This gene encodes a member of the zinc-iron permease family. The encoded protein is localized to the cell membrane and acts as a zinc uptake transporter. This gene has been linked to prostate cancer, breast cancer, and Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO27769 SLC39A1 Knockout cell line (HeLa) Human SLC39A1 1:3~1:6 Negative Online Inquiry
KO27770 SLC39A1 Knockout cell line (HCT 116) Human SLC39A1 1:2~1:4 Negative Online Inquiry
KO27771 SLC39A1 Knockout cell line (HEK293) Human SLC39A1 1:3~1:6 Negative Online Inquiry
KO27772 SLC39A1 Knockout cell line (A549) Human SLC39A1 1:3~1:4 Negative Online Inquiry

Background

SLC39A1 Gene Knockout Cell Lines are specialized cellular models developed to study the role of the SLC39A1 gene, which encodes a zinc transporter essential for cellular zinc homeostasis. These cell lines have been genetically modified to disrupt SLC39A1 expression, allowing researchers to investigate the implications of zinc transport dysregulation in various biological processes such as cellular growth, differentiation, and apoptosis.

The key function of these knockout cell lines lies in their ability to mimic pathophysiological conditions where SLC39A1 function is impaired. By eliminating the SLC39A1 gene, these models provide critical insights into how alterations in zinc levels affect signaling pathways, oxidative stress responses, and immune function. Researchers can utilize these knockout cell lines to explore a variety of applications, including cancer biology, neurodegenerative disorders, and nutrient sensing, thereby advancing the understanding of disease mechanisms and potential therapeutic targets.

The scientific importance of SLC39A1 Gene Knockout Cell Lines is underscored by their relevance in both fundamental research and clinical applications. Unlike traditional cell lines, these specialized models enable precise investigations into the effects of zinc deficiency or overload, allowing for a more nuanced understanding of its role in health and disease. This specificity is a significant advantage over alternatives that do not account for the nuanced genetic variations affecting zinc transport.

What sets our SLC39A1 Gene Knockout Cell Lines apart is their high reproducibility and validated performance, ensuring that researchers obtain consistent results critical for publication and therapeutic development. Additionally, they are accompanied by comprehensive technical support and cell culture guidelines, further simplifying the research process.

By choosing our SLC39A1 Gene Knockout Cell Lines, researchers and clinicians gain access to a cutting-edge tool essential for advancing their work in gene function studies and therapeutic innovation. Our company prides itself on its commitment to providing high-quality biological products, supported by a team of experts dedicated to enhancing research capabilities and outcomes.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.