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SLC35C1 Knockout Cell Lines

Gene: SLC35C1

Official Full Name: solute carrier family 35 member C1provided by HGNC

Gene Summary: This gene encodes a GDP-fucose transporter that is found in the Golgi apparatus. Mutations in this gene result in congenital disorder of glycosylation type IIc. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00968 SLC35C1 Knockout cell line (Hep G2) Human SLC35C1 1:2~1:4 Negative Online Inquiry
KO14029 SLC35C1 Knockout cell line (HeLa) Human SLC35C1 1:3~1:6 Negative Online Inquiry
KO14030 SLC35C1 Knockout cell line (HCT 116) Human SLC35C1 1:2~1:4 Negative Online Inquiry
KO14031 SLC35C1 Knockout cell line (HEK293) Human SLC35C1 1:3~1:6 Negative Online Inquiry
KO14032 SLC35C1 Knockout cell line (A549) Human SLC35C1 1:3~1:4 Negative Online Inquiry

Background

SLC35C1 Gene Knockout Cell Lines represent a cutting-edge tool in molecular biology research, specifically engineered to eliminate the SLC35C1 gene, which is implicated in various cellular processes, including nucleotide sugar transport and cellular signaling. By utilizing CRISPR-Cas9 technology, these cell lines provide a reliable model for studying the functional consequences of SLC35C1 deletion, enabling researchers to investigate its role in both normal physiology and disease states.

The key function of SLC35C1 knockout cells lies in their ability to shed light on glycosylation pathways and their impact on cellular functions such as immune response, cell adhesion, and signaling mechanisms. With the SLC35C1 gene silenced, researchers can assess changes in cellular behavior, gene expression profiles, and metabolic activities, thus advancing the understanding of its pathophysiological contributions, particularly in cancers and genetic disorders.

The scientific importance of these cell lines extends to their applications in research environments focused on cell biology, pharmacology, and therapeutic development. By providing a robust platform for in vitro studies, SLC35C1 knockout cell lines facilitate high-throughput screenings, drug targeting strategies, and pathway elucidation that are vital for advancing biomedical science.

Compared to alternative models, such as siRNA-mediated knockdown, SLC35C1 knockout cell lines offer permanent genetic modification, thereby ensuring stability over repeated experiments and reducing variability. This advantage is crucial for obtaining reproducible results, making them an invaluable asset for both basic research and translational applications.

Researchers and clinicians looking to deepen their understanding of glycosylation and its implications in health and disease will find SLC35C1 Gene Knockout Cell Lines to be an essential resource. Their reliability and comprehensiveness provide clear benefits in elucidating complex biological interactions and developing new therapeutic strategies.

At [Your Company Name], we pride ourselves on providing high-quality biological products designed for clarity and efficacy in scientific investigation. Our expertise in gene editing and cell line development ensures that researchers have access to the best tools available for their groundbreaking work.

Please note that all services are for research use only. Not intended for any clinical use.

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