Gene: SLC25A47
Official Full Name: solute carrier family 25 member 47provided by HGNC
Gene Summary: This gene encodes a member of a large family of mitochondrial transporters. The nuclear-encoded carrier protein is embedded in the inner mitochondrial membrane. This member of the family is thought to be an uncoupling protein that uncouples mitochondrial respiration from ATP synthesis by dissipating the transmembrane proton gradient. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2017]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO00072 | SLC25A47 Knockout cell line (Vips) | Human | SLC25A47 | Negative | Online Inquiry |
SLC25A47 Gene Knockout Cell Lines represent a cutting-edge tool in genetic and cellular research, designed to facilitate the study of the SLC25A47 gene, which encodes a mitochondrial transporter involved in metabolic regulations. These engineered cell lines enable researchers to investigate the functional consequences of SLC25A47 loss, providing insights into mitochondrial bioenergetics and cellular metabolism. By employing CRISPR/Cas9 technology for precise gene editing, these knockout cell lines exhibit complete disruption of SLC25A47 expression, creating a robust model for evaluating mitochondrial dynamics and the impact of its deficiency on cellular pathways.
The primary functions facilitated by SLC25A47 knockout include elucidating metabolic reprogramming, mitochondrial respiratory function, and potential stress responses. This knockout model is particularly valuable in cancer research, where altered metabolic pathways play a pivotal role in tumor growth and survival. Leveraging these cell lines allows scientists to investigate the implications of SLC25A47 in cancer metabolism, providing potential therapeutic targets for intervention.
The scientific importance of SLC25A47 Gene Knockout Cell Lines extends into both research and clinical settings, enabling the dissection of metabolic pathways in a variety of biological contexts, including neurodegenerative diseases and genetic disorders. Compared to traditional methods, such as siRNA-mediated knockdown, these knockout models offer enhanced specificity and stability, allowing for long-term studies without the challenges of transient gene expression changes.
For researchers and clinicians seeking a reliable resource in mitochondrial research and metabolic pathway analysis, SLC25A47 Gene Knockout Cell Lines provide significant advantages. They are tailored for high-throughput screening, live-cell imaging, and drug response assays, which streamline experimental workflows and improve data reproducibility.
Our company brings extensive expertise in genetic engineering and cell line development. With a commitment to delivering high-quality biological products, we ensure each cell line is meticulously validated for authenticity and performance, empowering researchers to advance their scientific inquiries with confidence.
Please note that all services are for research use only. Not intended for any clinical use.
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