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SLC10A4 Knockout Cell Lines

Gene: SLC10A4

Official Full Name: solute carrier family 10 member 4provided by HGNC

Gene Summary: Predicted to enable bile acid:sodium symporter activity. Predicted to be involved in bile acid and bile salt transport and regulation of neurotransmitter loading into synaptic vesicle. Predicted to act upstream of or within adult behavior and response to xenobiotic stimulus. Predicted to be located in plasma membrane. Predicted to be active in several cellular components, including dopaminergic synapse; serotonergic synapse; and synaptic vesicle membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO37097 SLC10A4 Knockout cell line (HCT 116) Human SLC10A4 1:2~1:4 Negative Online Inquiry
KO37098 SLC10A4 Knockout cell line (HEK293) Human SLC10A4 1:3~1:6 Negative Online Inquiry
KO37099 SLC10A4 Knockout cell line (A549) Human SLC10A4 1:3~1:4 Negative Online Inquiry

Background

SLC10A4 Gene Knockout Cell Lines are specifically engineered cellular models designed to investigate the function of the SLC10A4 gene, which encodes for a sodium-dependent transporter implicated in neurochemical modulation and metabolic processes. These cell lines have undergone precise genome editing, utilizing techniques such as CRISPR/Cas9, to permanently disrupt the expression of the SLC10A4 gene. This targeted knockout allows researchers to explore the physiological and pharmacological implications of SLC10A4 deficiency.

The primary function of the SLC10A4 gene product is to regulate the transport of neurotransmitters and metabolic substrates, thereby influencing synaptic transmission and energy metabolism. By utilizing these knockout cell lines, scientists can assess alterations in neurotransmitter uptake, signaling pathways, and metabolic responses that can occur as a result of impaired SLC10A4 function. This level of investigation is crucial for understanding various neurological conditions and metabolic disorders, paving the way for identifying potential therapeutic targets.

In research and clinical settings, SLC10A4 Gene Knockout Cell Lines are invaluable tools for drug discovery and validation, allowing for the assessment of pharmacological agents that may restore or counteract the effects of SLC10A4 loss. Compared to standard cell lines, these knockout models offer enhanced specificity and fidelity in illuminating the role of the SLC10A4 gene, providing researchers with rich, actionable insights that can drive innovation in treatment strategies.

What sets our SLC10A4 Gene Knockout Cell Lines apart from alternatives is their rigorous validation process and consistent performance across experiments, ensuring reliable experimental outcomes. This product is ideal for researchers focused on neurobiology, pharmacology, and metabolic studies, as it caters to the need for sophisticated models that reflect human disease biology.

Our company specializes in biological products and genetic engineering technologies, delivering high-quality tools tailored to meet the unique needs of the scientific community. By choosing SLC10A4 Gene Knockout Cell Lines, you are investing in a product that enhances your research capabilities and drives forward scientific understanding in critical health areas.

Please note that all services are for research use only. Not intended for any clinical use.

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