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SIDT2 Knockout Cell Lines

Gene: SIDT2

Official Full Name: SID1 transmembrane family member 2provided by HGNC

Gene Summary: Predicted to enable several functions, including AP-1 adaptor complex binding activity; AP-2 adaptor complex binding activity; and RNA transmembrane transporter activity. Involved in RNA transport. Located in lysosomal membrane and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00325 SIDT2 Knockout cell line (HeLa) Human SIDT2 1:3~1:6 Negative Online Inquiry
KO23064 SIDT2 Knockout cell line (HCT 116) Human SIDT2 1:2~1:4 Negative Online Inquiry
KO23065 SIDT2 Knockout cell line (HEK293) Human SIDT2 1:3~1:6 Negative Online Inquiry
KO23066 SIDT2 Knockout cell line (A549) Human SIDT2 1:3~1:4 Negative Online Inquiry

Background

SIDT2 Gene Knockout Cell Lines are specifically engineered cellular models in which the SIDT2 gene has been disrupted, creating a unique platform for investigating the functional roles of this gene in various biological processes. The SIDT2 gene encodes a protein involved in RNA transport and potential cellular signaling pathways, making it a crucial subject for research in gene expression regulation and cellular biology.

These knockout cell lines utilize CRISPR-Cas9 technology to achieve precise gene editing, ensuring that the absence of the SIDT2 gene is absolute, which allows researchers to meticulously study the effects on RNA metabolism and related cellular functions. The mechanism of action involves creating double-strand breaks in the DNA, followed by non-homologous end joining, which leads to the targeted gene's knockout. This technology not only enhances the specificity of the editing process but also enables the generation of cellular models that can accurately reflect the natural biological state devoid of the SIDT2 gene.

In scientific research and clinical settings, these knockout cell lines have immense significance. They provide insights into gene function related to disorders associated with RNA transport and can facilitate the identification of novel therapeutic targets. The SIDT2 knockout model is pivotal in studying diseases such as neurodegenerative disorders and cancer, where RNA processing plays a vital role in pathophysiology.

Compared to alternative gene disruption methods, SIDT2 Gene Knockout Cell Lines offer higher precision, efficiency, and reproducibility in research applications. Researchers benefit from ease of use, consistent results, and the ability to create stable lines for extended studies, making them invaluable tools in molecular biology and genetics research.

For scientists and clinicians looking to explore the complexities of gene function and its implications in health and disease, SIDT2 Gene Knockout Cell Lines represent an indispensable resource. Our commitment to providing high-quality biological products is backed by extensive expertise and innovation in genetic engineering, ensuring your research is supported by reliable, cutting-edge tools.

Please note that all services are for research use only. Not intended for any clinical use.

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