Gene: SH3GLB1
Official Full Name: SH3 domain containing GRB2 like, endophilin B1provided by HGNC
Gene Summary: This gene encodes a SRC homology 3 domain-containing protein. The encoded protein interacts with the proapoptotic member of the Bcl-2 family, Bcl-2-associated X protein (Bax) and may be involved in regulating apoptotic signaling pathways. This protein may also be involved in maintaining mitochondrial morphology. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23029 | SH3GLB1 Knockout cell line (HeLa) | Human | SH3GLB1 | 1:3~1:6 | Negative | Online Inquiry |
KO23030 | SH3GLB1 Knockout cell line (HCT 116) | Human | SH3GLB1 | 1:2~1:4 | Negative | Online Inquiry |
KO23031 | SH3GLB1 Knockout cell line (HEK293) | Human | SH3GLB1 | 1:3~1:6 | Negative | Online Inquiry |
KO23032 | SH3GLB1 Knockout cell line (A549) | Human | SH3GLB1 | 1:3~1:4 | Negative | Online Inquiry |
SH3GLB1 Gene Knockout Cell Lines represent a powerful genetic tool engineered to facilitate in-depth studies of the SH3GLB1 gene, which is critical for various cellular processes, including endocytosis and cellular signaling. These cell lines have been developed using advanced CRISPR/Cas9 technology to precisely disable the SH3GLB1 gene, allowing researchers to explore the functional consequences of its absence in diverse biological contexts.
The key function of these knockout cell lines lies in their ability to mimic the loss of SH3GLB1, enabling scientists to investigate cellular pathways and mechanisms influenced by this gene. By observing how cells respond to various stimuli or treatments in the absence of SH3GLB1, researchers can gain insights into the gene's role in normal cellular function as well as in disease states, including cancer and neurodegenerative disorders. These insights are invaluable in advancing therapeutic approaches and ultimately enhancing patient outcomes.
In research and clinical settings, these knockout cell lines are vital for validating drug targets and identifying potential biomarkers for disease progression. The specific advantages of our SH3GLB1 Gene Knockout Cell Lines include high efficiency and specificity of gene editing, well-characterized genetic backgrounds, and reproducibility across experiments. Unlike traditional knockdown approaches, which can lead to incomplete gene silencing and off-target effects, our knockout technology provides a robust model to study gene function comprehensively.
Researchers, clinicians, and biotechnology companies will find tremendous value in these cell lines as they pave the way for innovative discoveries and translational research. Our commitment to quality ensures that users receive rigorously validated products that meet the highest standards of scientific accuracy and reliability.
With a strong foundation in molecular biology and a focus on cutting-edge technologies, our company is dedicated to delivering exceptional biological tools that enhance research capabilities and open new avenues for scientific exploration.
Please note that all services are for research use only. Not intended for any clinical use.
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