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SH3D19 Knockout Cell Lines

Gene: SH3D19

Official Full Name: SH3 domain containing 19provided by HGNC

Gene Summary: This gene encodes a multiple SH3 domain-containing protein, which interacts with other proteins, such as EBP and members of ADAM family, via the SH3 domains. This protein may be involved in suppression of Ras-induced cellular transformation and Ras-mediated activation of ELK1 by EBP, and regulation of ADAM proteins in the signaling of EGFR-ligand shedding. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO21799 SH3D19 Knockout cell line (HeLa) Human SH3D19 1:3~1:6 Negative Online Inquiry
KO21800 SH3D19 Knockout cell line (HCT 116) Human SH3D19 1:2~1:4 Negative Online Inquiry
KO21801 SH3D19 Knockout cell line (HEK293) Human SH3D19 1:3~1:6 Negative Online Inquiry
KO21802 SH3D19 Knockout cell line (A549) Human SH3D19 1:3~1:4 Negative Online Inquiry

Background

SH3D19 Gene Knockout Cell Lines are genetically engineered cellular models specifically designed to provide researchers with a vital tool for elucidating the biological roles of the SH3D19 gene. Utilizing contemporary CRISPR-Cas9 technology, these cell lines have been meticulously created to disrupt the SH3D19 gene, enabling scientists to observe phenotypic changes and understand downstream signaling pathways. The knockout of SH3D19 can lead to alterations in various cellular processes, including metabolism, differentiation, and apoptosis, making these models invaluable for dissecting the gene’s function within cellular contexts.

One of the key mechanisms of action involves the permanent inactivation of SH3D19, allowing for detailed comparisons between wild-type and knockout cell lines. This comparison empowers researchers to explore the implications of SH3D19 deficiency in various physiological and pathological states, thus broadening the understanding of its contributions to diseases, particularly in cancer and metabolic disorders.

The scientific importance of SH3D19 Gene Knockout Cell Lines extends to diverse applications in both research and clinical settings, facilitating investigations into gene function, drug responses, and biomarker development. Exclusive to our product line, these cell lines are validated for robustness, reproducibility, and ease of use, ensuring that researchers can achieve reliable results that are pivotal for advancing their studies.

Furthermore, the specificity of our knockout models, combined with comprehensive user support and extensive documentation, provides significant advantages over alternative models such as RNA interference or pharmacological inhibitors, which may cause transient effects.

Researchers and clinicians will find the SH3D19 Gene Knockout Cell Lines to be an essential addition to their experimental toolkit, enabling deeper insights into gene regulation and therapeutic targets. With our company’s expertise in providing high-quality biological products and commitment to innovation, we ensure that our offerings meet the rigorous standards expected in contemporary scientific research.

Please note that all services are for research use only. Not intended for any clinical use.

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