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SH2D4A Knockout Cell Lines

Gene: SH2D4A

Official Full Name: SH2 domain containing 4Aprovided by HGNC

Gene Summary: Enables phosphatase binding activity. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14176 SH2D4A Knockout cell line (HeLa) Human SH2D4A 1:3~1:6 Negative Online Inquiry
KO14177 SH2D4A Knockout cell line (HCT 116) Human SH2D4A 1:2~1:4 Negative Online Inquiry
KO14178 SH2D4A Knockout cell line (HEK293) Human SH2D4A 1:3~1:6 Negative Online Inquiry
KO14179 SH2D4A Knockout cell line (A549) Human SH2D4A 1:3~1:4 Negative Online Inquiry

Background

SH2D4A Gene Knockout Cell Lines are genetically modified cell lines in which the SH2D4A gene has been specifically disrupted or deleted through targeted genome editing techniques, such as CRISPR-Cas9. This product serves as a vital tool for researchers aiming to study the function of the SH2D4A gene, which is implicated in various cellular processes including immune regulation and signal transduction.

The primary function of these knockout cell lines is to provide a model for investigating the physiological and pathological roles of the SH2D4A gene. By observing how these cells behave in the absence of SH2D4A, researchers can elucidate its contributions to cellular signaling pathways, immune responses, and disease states. The mechanisms through which SH2D4A operates highlight its significance in the context of T cell activation and its potential impact on autoimmune diseases, making these cell lines invaluable for both basic and applied research.

In clinical and research settings, the SH2D4A Gene Knockout Cell Lines facilitate the evaluation of drug candidates targeting related pathways, advancing our understanding of therapeutic interventions for disorders influenced by immune dysregulation. Additionally, these cell lines are critical for functional assays that assess the impact of SH2D4A on cellular phenotypes, making them essential for researchers working in immunology, oncology, and cell biology.

Compared to traditional knockout models that may involve complex animal studies, SH2D4A Gene Knockout Cell Lines offer several advantages, including reduced time and cost associated with animal care, better reproducibility of results, and the ability to perform high-throughput screening. This capability allows researchers to easily assess multiple compounds or conditions in a controlled in vitro environment.

For scientists, clinicians, and pharmaceutical developers, the value of the SH2D4A Gene Knockout Cell Lines cannot be overstated. They provide a robust platform for investigating gene function and potential therapeutic targets, supporting the advancement of medical science.

Our company prides itself on a commitment to excellence in genetic engineering and cell line development, ensuring that you have access to high-quality products that cater to the diverse needs of the scientific community.

Please note that all services are for research use only. Not intended for any clinical use.

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