Gene: SEPTIN3
Official Full Name: septin 3provided by HGNC
Gene Summary: This gene belongs to the septin family of GTPases. Members of this family are required for cytokinesis. Expression is upregulated by retinoic acid in a human teratocarcinoma cell line. The specific function of this gene has not been determined. Alternative splicing of this gene results in several transcript variants encoding different isoforms. [provided by RefSeq, May 2018]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO14214 | SEPTIN3 Knockout cell line (HCT 116) | Human | SEPTIN3 | 1:2~1:4 | Negative | Online Inquiry |
KO14215 | SEPTIN3 Knockout cell line (HEK293) | Human | SEPTIN3 | 1:3~1:6 | Negative | Online Inquiry |
KO14216 | SEPTIN3 Knockout cell line (A549) | Human | SEPTIN3 | 1:3~1:4 | Negative | Online Inquiry |
SEPTIN3 Gene Knockout Cell Lines are specialized cellular tools engineered to specifically disrupt the function of the SEPTIN3 gene, which encodes a member of the septin family of GTP-binding proteins. These cell lines provide researchers with a robust model for investigating the role of SEPTIN3 in cellular processes, such as cytokinesis, membrane dynamics, and signal transduction. By introducing a targeted knockout, these cell lines allow for the analysis of the phenotypic consequences of SEPTIN3 ablation and its implications in various biological pathways.
The key function of the SEPTIN3 Gene Knockout Cell Lines lies in their capacity to facilitate the dissection of the role of septins in cellular architecture and function. SEPTIN3 has been implicated in cytoskeletal organization, cell division, and maintaining cellular integrity. The knockout mechanism is achieved through state-of-the-art genome editing techniques, ensuring specificity and reproducibility, which are crucial for producing reliable experimental data.
The scientific importance of these cell lines cannot be overstated. They serve as valuable models in research aimed at understanding tumor biology, neurological conditions, and other diseases in which septins play a critical role. In clinical settings, insights derived from experiments using SEPTIN3 knockout lines can lead to the identification of novel therapeutic targets and the development of innovative treatment strategies.
Compared to alternative models, such as wild-type cell lines or conventional knockdown systems utilizing RNA interference, SEPTIN3 Gene Knockout Cell Lines provide a permanent and complete disruption of the gene function. This offers enhanced clarity in experimental outcomes and avoids confounding variables associated with temporary knockdowns, thus ensuring that data obtained are directly attributable to the loss of SEPTIN3.
For researchers and clinicians, the value of SEPTIN3 Gene Knockout Cell Lines lies in their ability to generate precise data that advance our understanding of complex biological systems. By utilizing these specialized cell lines, scientists can uncover mechanisms of disease and contribute to the development of future therapeutic interventions.
With our extensive background in developing high-quality biological products and a commitment to advancing scientific research, our offerings, including the SEPTIN3 Gene Knockout Cell Lines, are designed to meet the evolving needs of the research community.
Please note that all services are for research use only. Not intended for any clinical use.
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