Gene: SELENBP1
Official Full Name: selenium binding protein 1provided by HGNC
Gene Summary: This gene encodes a member of the selenium-binding protein family. Selenium is an essential nutrient that exhibits potent anticarcinogenic properties, and deficiency of selenium may cause certain neurologic diseases. The effects of selenium in preventing cancer and neurologic diseases may be mediated by selenium-binding proteins, and decreased expression of this gene may be associated with several types of cancer. The encoded protein may play a selenium-dependent role in ubiquitination/deubiquitination-mediated protein degradation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2012]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO00960 | SELENBP1 Knockout cell line (HT-29) | Human | SELENBP1 | 1:2~1:4 | Negative | Online Inquiry |
KO06149 | SELENBP1 Knockout cell line (HeLa) | Human | SELENBP1 | 1:3~1:6 | Negative | Online Inquiry |
KO06150 | SELENBP1 Knockout cell line (HEK293) | Human | SELENBP1 | 1:3~1:6 | Negative | Online Inquiry |
KO06151 | SELENBP1 Knockout cell line (A549) | Human | SELENBP1 | 1:3~1:4 | Negative | Online Inquiry |
SELENBP1 Gene Knockout Cell Lines are genetically engineered cell models designed to facilitate the study of the selenoprotein-binding protein 1 (SELENBP1) gene. This product is created via precise gene-editing techniques, such as CRISPR-Cas9, allowing for the complete ablation of SELENBP1 in cultured cells. The resultant knockout cell lines provide a robust platform for investigating the functional roles of SELENBP1, particularly in the context of selenium metabolism and cellular redox balance.
The key function of these knockout cell lines lies in their ability to elucidate the molecular mechanisms by which SELENBP1 influences selenoprotein synthesis, cellular stress response, and overall metabolic health. Researchers can analyze the phenotypic changes resulting from the gene inactivation, providing insight into the gene's role in various biological processes and disease states, including cancer and neurodegenerative disorders.
In terms of scientific importance, these cell lines expand the toolkit available to researchers studying SELENBP1-related pathways in both basic and applied scientific research. Applications range from functional genomics to drug development, enabling the identification of novel therapeutic targets and biomarkers. Additionally, with the rising interest in selenium's effects on human health, these models are particularly relevant for exploring dietary supplementation strategies and genetic predispositions to selenium deficiency-related diseases.
What sets SELENBP1 Gene Knockout Cell Lines apart from alternative models is their tailored specificity and the assurance of complete gene disruption, which ensures reliable and reproducible experimental outcomes. Furthermore, they come with comprehensive support from our research and development team, including protocols and application guidance, facilitating seamless integration into existing workflows.
Researchers and clinicians can enhance their investigations and interventions by utilizing SELENBP1 Gene Knockout Cell Lines, making valuable contributions to the understanding of selenium's multifaceted roles in health and disease. Our commitment to excellence in genetic model development stems from years of expertise in biological research, ensuring that you receive high-quality products tailored to your experimental needs.
Please note that all services are for research use only. Not intended for any clinical use.
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