Gene: SEC14L2
Official Full Name: SEC14 like lipid binding 2provided by HGNC
Gene Summary: This gene encodes a cytosolic protein which belongs to a family of lipid-binding proteins including Sec14p, alpha-tocopherol transfer protein, and cellular retinol-binding protein. The encoded protein stimulates squalene monooxygenase which is a downstream enzyme in the cholesterol biosynthetic pathway. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO29172 | SEC14L2 Knockout cell line (HeLa) | Human | SEC14L2 | 1:3~1:6 | Negative | Online Inquiry |
KO29173 | SEC14L2 Knockout cell line (HCT 116) | Human | SEC14L2 | 1:2~1:4 | Negative | Online Inquiry |
KO29174 | SEC14L2 Knockout cell line (HEK293) | Human | SEC14L2 | 1:3~1:6 | Negative | Online Inquiry |
KO29175 | SEC14L2 Knockout cell line (A549) | Human | SEC14L2 | 1:3~1:4 | Negative | Online Inquiry |
SEC14L2 Gene Knockout Cell Lines are a cutting-edge biological product engineered to provide researchers with a unique tool for studying the functional consequences of SEC14L2 gene disruption. SEC14L2, or SEC14-like 2, is known to be involved in lipid metabolism and cellular signaling pathways, and its knockout enables the investigation of its role in various physiological and pathological processes. The development of these cell lines employs advanced CRISPR-Cas9 technology, allowing for precise gene editing that results in the complete knockout of SEC14L2, creating a controlled environment for experimental manipulation.
The primary mechanism of action involves the disruption of the SEC14L2 gene, which may alter lipid droplet dynamics and phospholipid distribution within the cell. By understanding how these changes influence cellular behaviors—such as proliferation, apoptosis, and metabolic dysregulation—researchers can glean insights into conditions like metabolic syndrome, cancer, and neurodegenerative diseases. The ability to analyze SEC14L2's role in these contexts establishes its significance in both research and clinical settings, paving the way for novel therapeutic strategies.
What sets our SEC14L2 Gene Knockout Cell Lines apart from other genetic models is their robust validation and characterization, ensuring reproducibility and reliability in experimental results. Our product is generated from well-established cell lines, providing a familiar platform to scientists while reducing the time and resources typically needed for custom model development.
Researchers and clinicians will find these cell lines invaluable for advancing their studies and developing therapeutic interventions. The accessibility of these knockout models empowers scientists to delve deeper into lipid metabolism research with minimal technical hurdles.
With our extensive expertise in genetic engineering and commitment to delivering high-quality biological products, our company stands at the forefront of innovation, ensuring reliable tools are available to the scientific community to drive discoveries in genetics and molecular biology.
Please note that all services are for research use only. Not intended for any clinical use.
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