Home / SCNN1D Knockout Cell Lines

SCNN1D Knockout Cell Lines

Gene: SCNN1D

Official Full Name: sodium channel epithelial 1 subunit deltaprovided by HGNC

Gene Summary: Enables sodium channel activity. Involved in cellular response to acidic pH; intracellular sodium ion homeostasis; and sodium ion import across plasma membrane. Located in actin cytoskeleton and membrane. Part of sodium channel complex. Is active in apical plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO03384 SCNN1D Knockout cell line (HeLa) Human SCNN1D 1:3~1:6 Negative Online Inquiry
KO03385 SCNN1D Knockout cell line (HCT 116) Human SCNN1D 1:2~1:4 Negative Online Inquiry
KO03386 SCNN1D Knockout cell line (HEK293) Human SCNN1D 1:3~1:6 Negative Online Inquiry
KO03387 SCNN1D Knockout cell line (A549) Human SCNN1D 1:3~1:4 Negative Online Inquiry

Background

SCNN1D Gene Knockout Cell Lines represent a specialized set of genetically engineered cellular models designed to investigate the function of the SCNN1D gene, which encodes the delta subunit of the epithelial sodium channel (ENaC). These knockout cell lines are created by employing advanced genome-editing techniques, such as CRISPR-Cas9, to precisely ablate the SCNN1D gene, thereby providing a powerful tool for researchers studying sodium transport, electrolyte balance, and related physiological processes.

The primary function of SCNN1D Gene Knockout Cell Lines is to serve as a model system for observing the physiological and molecular consequences of SCNN1D gene disruption. By removing this gene, researchers can evaluate alterations in cellular ion homeostasis and explore the subsequent effects on extracellular fluid volume, blood pressure regulation, and pulmonary function. This tool is invaluable in both academic and clinical research settings, particularly in studies focused on cardiovascular health, respiratory diseases, and conditions related to sodium reabsorption dysfunction.

One of the significant advantages of using SCNN1D Gene Knockout Cell Lines lies in their specificity and reliability compared to other models, such as animal studies or non-targeted cell lines. These knockout cells allow for controlled experiments in a simplified environment, enabling researchers to isolate the effects of the SCNN1D gene. Furthermore, their use can accelerate the understanding of diseases linked to sodium imbalance, paving the way for novel therapeutic strategies.

For researchers and clinicians, the ability to delve deeper into the role of the SCNN1D gene enhances our understanding of critical biological processes that underlie various diseases. This genomic tool not only supports hypothesis-driven research but also facilitates the development of potential interventions.

Our company prides itself on its commitment to advancing scientific research through the provision of high-quality biological products. With a focus on precision and innovation, we ensure that our offerings, including the SCNN1D Gene Knockout Cell Lines, are meticulously validated and tailored to meet the evolving needs of the research community.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.