Gene: SCAMP3
Official Full Name: secretory carrier membrane protein 3provided by HGNC
Gene Summary: This gene encodes an integral membrane protein that belongs to the secretory carrier membrane protein family. The encoded protein functions as a carrier to the cell surface in post-golgi recycling pathways. This protein is also involved in protein trafficking in endosomal pathways. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO32333 | SCAMP3 Knockout cell line (HeLa) | Human | SCAMP3 | 1:3~1:6 | Negative | Online Inquiry |
KO32334 | SCAMP3 Knockout cell line (HCT 116) | Human | SCAMP3 | 1:2~1:4 | Negative | Online Inquiry |
KO32335 | SCAMP3 Knockout cell line (HEK293) | Human | SCAMP3 | 1:3~1:6 | Negative | Online Inquiry |
KO32336 | SCAMP3 Knockout cell line (A549) | Human | SCAMP3 | 1:3~1:4 | Negative | Online Inquiry |
SCAMP3 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to facilitate the study of the SCAMP3 (Secretory Carrier Membrane Protein 3) gene and its role in cellular processes. These cell lines have been generated using advanced CRISPR/Cas9 technology, resulting in precise gene deletions that eliminate the expression of the SCAMP3 protein. By creating these knockout models, researchers can investigate the downstream effects of SCAMP3 loss on cellular function, including endocytosis, vesicle trafficking, and membrane dynamics.
The primary mechanism of action involves the disruption of the SCAMP3 gene locus, leading to a lack of functional protein that can be identified through assays measuring vesicular transport and membrane integrity. This creates an invaluable pathway for understanding various physiological and pathological states where SCAMP3 is implicated, such as neurodegenerative diseases and certain cancers. The importance of SCAMP3 in the regulation of membrane recycling in secretory pathways further underscores its potential as a target for therapeutic interventions and drug discovery processes.
SCAMP3 Gene Knockout Cell Lines offer several advantages over traditional gene manipulation techniques. Notably, they provide a stable and consistent model for experimental replications, significantly reducing the variable outcomes associated with transient transfections or chemical inhibitors. This consistency enhances data reliability, making it easier for researchers to draw meaningful conclusions from their experiments. Furthermore, these knockout cell lines are ready-to-use, streamlining the setup process for new studies and saving researchers valuable time.
For researchers and clinicians focusing on cellular biology, these cell lines represent a unique and powerful tool. They enable the exploration of fundamental biological questions and the development of novel therapies more efficiently than ever before. With a commitment to genetic engineering and cell line development, our company stands at the forefront of scientific innovation, providing top-tier products that support groundbreaking discoveries in biomedical research.
Please note that all services are for research use only. Not intended for any clinical use.
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