Gene: SCAF8
Official Full Name: SR-related CTD associated factor 8provided by HGNC
Gene Summary: Enables RNA binding activity and RNA polymerase II C-terminal domain phosphoserine binding activity. Involved in negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled and positive regulation of DNA-templated transcription, elongation. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO30285 | SCAF8 Knockout cell line (HeLa) | Human | SCAF8 | 1:3~1:6 | Negative | Online Inquiry |
KO30286 | SCAF8 Knockout cell line (HCT 116) | Human | SCAF8 | 1:2~1:4 | Negative | Online Inquiry |
KO30287 | SCAF8 Knockout cell line (HEK293) | Human | SCAF8 | 1:3~1:6 | Negative | Online Inquiry |
KO30288 | SCAF8 Knockout cell line (A549) | Human | SCAF8 | 1:3~1:4 | Negative | Online Inquiry |
SCAF8 Gene Knockout Cell Lines represent a cutting-edge tool in the study of gene function and cellular processes. These cell lines have been genetically engineered to effectively silence the SCAF8 gene, a critical component in cellular signaling, differentiation, and apoptosis. The knockout of this gene allows researchers to investigate the biological roles that SCAF8 plays in various pathways and disease states, facilitating a deeper understanding of its contributions to cellular behavior and pathology.
The primary mechanism by which these cell lines operate involves the application of CRISPR-Cas9 technology, which enables precise editing of the genome. By introducing targeted mutations in the SCAF8 locus, researchers achieve a complete disruption of the gene's expression, yielding valuable models that can mimic specific conditions related to cancer, neurodegenerative diseases, or developmental disorders. This tool is invaluable in elucidating the underlying mechanisms of these conditions, allowing for the development of targeted therapies and personalized medicine approaches.
In both research and clinical settings, SCAF8 Gene Knockout Cell Lines provide significant advantages over traditional cell models. These include enhanced specificity in the study of gene function, reduced off-target effects, and consistent reproducibility of results. Additionally, these knockout lines allow for straightforward comparisons with wild-type cell lines, enhancing the clarity of experimental outcomes. Their use can lead to more efficient drug screening and development processes, making them a vital resource for academic researchers and biotechnology firms alike.
For researchers and clinicians looking to explore the nuances of gene function and its implications in health and disease, SCAF8 Gene Knockout Cell Lines offer an unparalleled advantage. By leveraging our expertise in genomic technologies and a commitment to quality, we ensure that our products provide reliable, robust results that drive innovation in your research initiatives. Our dedication to advancing biological research is underscored by our continuous support for the scientific community's quest for discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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