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SALL1 Knockout Cell Lines

Gene: SALL1

Official Full Name: spalt like transcription factor 1provided by HGNC

Gene Summary: The protein encoded by this gene is a zinc finger transcriptional repressor and may be part of the NuRD histone deacetylase complex (HDAC). Defects in this gene are a cause of Townes-Brocks syndrome (TBS) as well as bronchio-oto-renal syndrome (BOR). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO35527 SALL1 Knockout cell line (HEK293) Human SALL1 1:3~1:6 Negative Online Inquiry

Background

SALL1 Gene Knockout Cell Lines are specially engineered cellular models that exhibit a complete knockout of the SALL1 gene, known for its crucial role in cell development and differentiation processes. This product employs advanced CRISPR-Cas9 technology to precisely delete the SALL1 gene, allowing researchers to study the consequences of its absence in various biological contexts.

The primary function of these knockout cell lines is to enable in-depth investigation of SALL1's involvement in essential cellular processes, such as embryogenesis and organogenesis. By studying these cells, researchers can elucidate the mechanisms underlying developmental disorders associated with SALL1 mutations, gaining insights into the gene's regulatory networks and its impact on stem cell behavior and differentiation pathways.

Scientifically, SALL1 gene knockout models hold significant importance in both research and clinical applications. They are invaluable for validating hypotheses related to SALL1-linked diseases, understanding its role in renal development, and exploring potential therapeutic strategies targeting the downstream effects of its absence. These cell lines can potentially inform the design of novel intervention strategies in regenerative medicine and developmental therapeutics.

What sets SALL1 Gene Knockout Cell Lines apart from alternatives is their high fidelity and reproducibility, alongside the ease of integration into existing experimental workflows. Users can derive fast and reliable insights into gene function, significantly reducing time and resource expenditure compared to classical gene manipulation techniques.

For researchers and clinicians seeking to deepen their understanding of the SALL1 gene and its physiological implications, our product offers a robust platform for discovery and innovation. The expertise of our company in developing genetically modified cell lines guarantees the highest quality and performance, ensuring that your research is built on a foundation of reliability and scientific rigor.

Please note that all services are for research use only. Not intended for any clinical use.

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