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RTN4RL2 Knockout Cell Lines

Gene: RTN4RL2

Official Full Name: reticulon 4 receptor like 2provided by HGNC

Gene Summary: Enables signaling receptor activity. Predicted to be involved in cell surface receptor signaling pathway; corpus callosum development; and negative regulation of neuron projection development. Located in cell surface and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14394 RTN4RL2 Knockout cell line (HCT 116) Human RTN4RL2 1:2~1:4 Negative Online Inquiry
KO14395 RTN4RL2 Knockout cell line (HEK293) Human RTN4RL2 1:3~1:6 Negative Online Inquiry
KO14396 RTN4RL2 Knockout cell line (A549) Human RTN4RL2 1:3~1:4 Negative Online Inquiry

Background

RTN4RL2 Gene Knockout Cell Lines are genetically engineered model systems that feature a knockout of the RTN4RL2 gene, which encodes a member of the reticulon family of proteins known to be involved in neuronal development and health. These cell lines serve as indispensable tools for exploring the functional implications of RTN4RL2 depletion in various biological contexts, particularly in neurobiology and cancer research.

The primary mechanism of action involves the disruption of the RTN4RL2 gene, leading to altered cellular pathways associated with neurite outgrowth, apoptosis, and cellular signaling. Researchers can utilize these knockout cell lines to investigate how the absence of RTN4RL2 affects cellular behavior, morphology, and gene expression profiles. This can elucidate its role in diseases such as neurodegenerative disorders and tumors, advancing our understanding of pathophysiological processes.

The scientific importance of RTN4RL2 Gene Knockout Cell Lines lies in their ability to bridge the gap between basic research and clinical applications. They provide crucial insights into the molecular mechanisms of disease, fostering the development of targeted therapies and diagnostics. Specifically, these cell lines enable high-throughput screening and validation of therapeutic compounds, thereby accelerating the drug discovery process.

What sets our RTN4RL2 Gene Knockout Cell Lines apart from conventional models is their validated genetic modification, which ensures consistent and reproducible results. In contrast to primary cells or transgenic models, these knockout lines offer researchers a controllable and homogenous system to study gene function without the variability associated with in vivo models.

For researchers and clinicians, the ability to precisely model RTN4RL2 function can lead to novel insights into therapeutic strategies and encourage further exploration of gene-targeting technologies. Our company's expertise in the development and maintenance of genetically modified cell lines guarantees that customers receive high-quality products tailored for exceptional research outcomes. With our commitment to biological innovation, we provide researchers with the essential tools to propel their inquiries into the mysteries of gene function and cellular regulation.

Please note that all services are for research use only. Not intended for any clinical use.

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