Gene: RSPH14
Official Full Name: radial spoke head 14 homologprovided by HGNC
Gene Summary: This gene encodes a protein with no known function but with slight similarity to a yeast vacuolar protein. The gene is located in a region deleted in pediatric rhabdoid tumors of the brain, kidney and soft tissues, but mutations in this gene have not been associated with the disease. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO27783 | RSPH14 Knockout cell line (HCT 116) | Human | RSPH14 | 1:2~1:4 | Negative | Online Inquiry |
KO27784 | RSPH14 Knockout cell line (A549) | Human | RSPH14 | 1:3~1:4 | Negative | Online Inquiry |
RSPH14 Gene Knockout Cell Lines are specialized biological reagents designed to facilitate the study of the RSPH14 gene's role in cellular processes and disease mechanisms. These cell lines have been genetically engineered to lack functional copies of the RSPH14 gene, enabling researchers to investigate its functions and implications in a controlled environment. Utilizing CRISPR/Cas9 technology, the knockout process ensures precise gene editing, leading to the effective silencing of the RSPH14 gene and allowing for the examination of phenotypic changes associated with its absence.
The primary function of the RSPH14 Gene Knockout Cell Lines is to serve as powerful tools in molecular biology, particularly in investigating the role of RSPH14 in ciliary function and related signaling pathways. Defects in ciliary function are linked to various human diseases, including respiratory and developmental disorders. By studying these cell lines, researchers can gain insights into the molecular mechanisms of disease, paving the way for potential therapeutic strategies.
From a scientific perspective, RSPH14 Gene Knockout Cell Lines play a crucial role in advancing our understanding of gene function and epigenetic regulation. They can be used in a variety of applications, including drug discovery, gene therapy evaluation, and basic research into cellular signaling pathways. Compared to alternative models, such as wild-type cell lines or less precise knockdown methods, these knockout cell lines offer superior specificity in studying gene function and a reliable means of modeling genetic diseases.
For researchers and clinicians alike, the accessibility of RSPH14 Gene Knockout Cell Lines represents an invaluable resource. They enable targeted studies that can lead to groundbreaking discoveries in genetics and cellular biology, thus informing clinical approaches to treating diseases associated with ciliary dysfunction.
Our company prides itself on delivering high-quality biological products with a commitment to innovation and reliability. With extensive expertise in gene editing technologies and a focus on advancing research capabilities, we offer a portfolio that empowers scientists to drive their research forward with confidence.
Please note that all services are for research use only. Not intended for any clinical use.
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