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RPS4Y1 Knockout Cell Lines

Gene: RPS4Y1

Official Full Name: ribosomal protein S4 Y-linked 1provided by HGNC

Gene Summary: Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes ribosomal protein S4, a component of the 40S subunit. Ribosomal protein S4 is the only ribosomal protein known to be encoded by more than one gene, namely this gene and ribosomal protein S4, X-linked (RPS4X). The 2 isoforms encoded by these genes are not identical, but are functionally equivalent. Ribosomal protein S4 belongs to the S4E family of ribosomal proteins. It has been suggested that haploinsufficiency of the ribosomal protein S4 genes plays a role in Turner syndrome; however, this hypothesis is controversial. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO35575 RPS4Y1 Knockout cell line (HCT 116) Human RPS4Y1 1:2~1:4 Negative Online Inquiry
KO35576 RPS4Y1 Knockout cell line (A549) Human RPS4Y1 1:3~1:4 Negative Online Inquiry

Background

RPS4Y1 Gene Knockout Cell Lines are advanced research tools developed to investigate the role of the RPS4Y1 gene, which encodes a ribosomal protein that is critical for the assembly of ribosomes and protein synthesis. These cell lines are engineered to lack the RPS4Y1 gene, enabling researchers to study the effects of its absence on cellular mechanisms, growth, and differentiation.

The primary function of these knockout cell lines lies in their capacity to provide insights into gene function through phenotypic analysis. By comparing the knockout cells with wild-type counterparts, scientists can elucidate the biological roles of RPS4Y1 within cellular processes, including stress responses, metabolic pathways, and developmental biology. The precise gene knockout technique employed ensures complete ablation of the target gene, allowing for accurate investigations into its contributions to cellular homeostasis and behavior.

RPS4Y1 knockout cell lines hold significant scientific importance, particularly in fields such as genetics, molecular biology, and therapeutic research. They serve as invaluable models for studying sex-related gene activity, understanding genetic disorders associated with the Y chromosome, and developing targeted interventions in diseases linked to ribosomal dysfunctions.

One of the unique advantages of RPS4Y1 Gene Knockout Cell Lines is their specificity and reliability, which surpasses traditional methods, such as siRNA or CRISPR-Cas9 approaches, by providing a stable cell line with consistent gene expression profiles. This stability allows for long-term studies and reproducibility, which are crucial in rigorous scientific research.

Researchers and clinicians will find these knockout cell lines valuable as they facilitate a deeper understanding of fundamental biological processes and contribute to the development of innovative therapeutic strategies. By employing these model systems, they can uncover potential treatment pathways for various genetic disorders, enhancing our overall understanding of human health.

Our company specializes in the production of high-quality biological research tools, and our RPS4Y1 Gene Knockout Cell Lines exemplify our commitment to supporting the scientific community with exceptional products designed for advanced research applications.

Please note that all services are for research use only. Not intended for any clinical use.

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