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RPP25 Knockout Cell Lines

Gene: RPP25

Official Full Name: ribonuclease P/MRP subunit p25provided by HGNC

Gene Summary: Enables ribonuclease P RNA binding activity. Contributes to ribonuclease P activity. Involved in tRNA 5'-leader removal. Located in centriolar satellite and nucleoplasm. Part of multimeric ribonuclease P complex and ribonuclease MRP complex. Biomarker of autistic disorder. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14429 RPP25 Knockout cell line (HeLa) Human RPP25 1:3~1:6 Negative Online Inquiry
KO14430 RPP25 Knockout cell line (HCT 116) Human RPP25 1:2~1:4 Negative Online Inquiry
KO14431 RPP25 Knockout cell line (HEK293) Human RPP25 1:3~1:6 Negative Online Inquiry
KO14432 RPP25 Knockout cell line (A549) Human RPP25 1:3~1:4 Negative Online Inquiry

Background

RPP25 Gene Knockout Cell Lines are genetically engineered cellular models designed to elucidate the role of the Ribonuclease P Protein Subunit 25 (RPP25) in various biological processes. These cell lines are characterized by the targeted disruption of the RPP25 gene, enabling researchers to investigate its function and implications in cellular mechanisms, particularly those related to RNA processing and maturation. By utilizing CRISPR/Cas9 technology, we ensure precise genetic modifications, facilitating robust studies on the impact of RPP25 absence on cellular physiology.

The primary function of these knockout cell lines lies in their capacity to provide insight into the molecular pathways associated with RPP25. The absence of RPP25 allows researchers to assess the resulting changes in ribonucleoprotein complex formation and RNA metabolism, thus expanding our understanding of gene expression regulation. In addition, these cell lines serve as critical tools in exploring the implications of RPP25 in disease models, such as cancer and autoimmune disorders, where dysregulated RNA processing can lead to aberrant cellular behavior.

Scientific importance is evident in both research and clinical applications. For instance, RPP25 knockout models can assist in drug development by providing information on potential therapeutic targets. Additionally, these cell lines may enable the validation of biomarkers for pathologies associated with RNA processing defects, offering clinicians novel avenues for diagnosis and treatment strategies.

What distinguishes RPP25 Gene Knockout Cell Lines from existing alternatives is our commitment to high-quality biological reagents: our cell lines are rigorously validated for stability, specificity, and reproducibility. This ensures that researchers can achieve consistent results, which are paramount in advancing scientific knowledge.

In sum, these knockout cell lines are invaluable assets for researchers and clinicians alike, offering the possibility to uncover innovative insights into gene function and its role in human health. With extensive expertise in molecular biology and genetic engineering, our company is dedicated to providing premium biological products that empower the scientific community in their quest for discovery and innovation.

Please note that all services are for research use only. Not intended for any clinical use.

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