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RNFT1 Knockout Cell Lines

Gene: RNFT1

Official Full Name: ring finger protein, transmembrane 1provided by HGNC

Gene Summary: Enables ubiquitin binding activity and ubiquitin protein ligase activity. Involved in positive regulation of ERAD pathway and protein autoubiquitination. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22963 RNFT1 Knockout cell line (HeLa) Human RNFT1 1:3~1:6 Negative Online Inquiry
KO22964 RNFT1 Knockout cell line (HCT 116) Human RNFT1 1:2~1:4 Negative Online Inquiry
KO22965 RNFT1 Knockout cell line (HEK293) Human RNFT1 1:3~1:6 Negative Online Inquiry
KO22966 RNFT1 Knockout cell line (A549) Human RNFT1 1:3~1:4 Negative Online Inquiry

Background

RNFT1 Gene Knockout Cell Lines are meticulously engineered cellular models specifically designed to investigate the functional role of the RNFT1 gene. This gene is known to be involved in various cellular processes, including stress response and intracellular signaling pathways. By employing CRISPR/Cas9 genome-editing technology, these cell lines have been developed to produce complete loss-of-function mutations of the RNFT1 gene, enabling researchers to study the resultant phenotypic changes and their underlying mechanisms.

The primary function of the RNFT1 gene knockout is to allow scientists to examine the effects of RNFT1 depletion across multiple biological contexts. This includes elucidation of its role in cellular stress responses, proliferation, and apoptosis. The knockout models facilitate comprehensive studies into how the absence of RNFT1 impacts signaling pathways, metabolic activities, and the cell's overall health profile, thereby advancing our understanding of its contribution to various diseases.

The scientific importance of RNFT1 Gene Knockout Cell Lines lies in their application in both research and clinical settings. They are invaluable tools for drug discovery, therapeutic target validation, and basic research aimed at unraveling disease mechanisms. By utilizing these knockout models, researchers can identify potential biomarkers and develop new therapeutic strategies for conditions associated with RNFT1 dysregulation.

One of the key advantages of our RNFT1 Gene Knockout Cell Lines is their high specificity and reliability compared to alternative methods such as siRNA knockdown or pharmacological inhibitors, which may have off-target effects. Our cell lines offer a stable and reproducible system for studying gene function while minimizing potential variability, thus yielding more consistent and interpretable results.

In an era where precision medicine is paramount, these knockout cell lines provide a robust platform for researchers and clinicians who are focused on genetic and molecular pathways. Their ability to facilitate targeted investigations makes them a valuable asset in deriving insights that can lead to innovative therapeutic interventions.

Our company prides itself on extensive expertise in cellular model development, backed by a commitment to quality and scientific rigor. By providing RNFT1 Gene Knockout Cell Lines, we offer researchers the tools necessary to explore complex biological questions and drive forward the frontiers of biomedical science.

Please note that all services are for research use only. Not intended for any clinical use.

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