Gene: RND1
Official Full Name: Rho family GTPase 1provided by HGNC
Gene Summary: This gene encodes a protein that belongs to the Rho GTPase family. Members of this family regulate the organization of the actin cytoskeleton in response to extracellular growth factors. A similar protein in rat interacts with a microtubule regulator to control axon extension. [provided by RefSeq, Apr 2014]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO27688 | RND1 Knockout cell line (HCT 116) | Human | RND1 | 1:2~1:4 | Negative | Online Inquiry |
KO27689 | RND1 Knockout cell line (HEK293) | Human | RND1 | 1:3~1:6 | Negative | Online Inquiry |
KO27690 | RND1 Knockout cell line (A549) | Human | RND1 | 1:3~1:4 | Negative | Online Inquiry |
RND1 Gene Knockout Cell Lines are specialized cellular models that have been genetically modified to permanently inactivate the RND1 gene, a crucial component in the regulation of actin dynamics and cellular signaling pathways. By employing the CRISPR-Cas9 genome editing technology, these cell lines provide researchers with a powerful tool to investigate the biological roles of RND1 in various cellular processes including growth, differentiation, and migration. The knockout of this gene allows for the study of its downstream effects, thereby providing insights into key pathological conditions such as cancer, neurodegenerative diseases, and cardiovascular disorders.
In terms of functionality, RND1 Gene Knockout Cell Lines enable the elucidation of genetic and molecular mechanisms by facilitating loss-of-function studies. Researchers can assess alterations in cellular behavior, signaling pathways, and gene expression patterns caused by the absence of RND1. These insights are particularly valuable in pharmaceutical developments, where understanding the implications of RND1 loss on drug response can inform therapeutic strategies.
The scientific importance of these cell lines extends to both research and clinical applications. In basic research, they serve as a model to simulate specific disease conditions, making them essential for the exploration of new therapeutic targets. In clinical settings, they can be instrumental in the development of gene therapies and personalized medicine approaches, where RND1 signaling might play a role in patient-specific treatments.
What sets our RND1 Gene Knockout Cell Lines apart from alternatives is their high specificity and reproducibility, achieved through optimized CRISPR designs and rigorous validation processes. Moreover, our cell lines are produced under stringent quality control measures, ensuring that they perform consistently across experiments, which is crucial for obtaining reliable and replicable results.
In choosing our RND1 Gene Knockout Cell Lines, researchers and clinicians gain access to invaluable resources that enhance their studies, streamline experimental workflows, and ultimately contribute to advancing our understanding of complex biological systems. Our company specializes in providing high-quality biological products tailored for innovative research and is committed to supporting scientific endeavors through our extensive expertise in genomic technologies and cell line development.
Please note that all services are for research use only. Not intended for any clinical use.
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