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RHOD Knockout Cell Lines

Gene: RHOD

Official Full Name: ras homolog family member Dprovided by HGNC

Gene Summary: Ras homolog, or Rho, proteins interact with protein kinases and may serve as targets for activated GTPase. They play a critical role in muscle differentiation. The protein encoded by this gene binds GTP and is a member of the small GTPase superfamily. It is involved in endosome dynamics and reorganization of the actin cytoskeleton, and it may coordinate membrane transport with the function of the cytoskeleton. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO26869 RHOD Knockout cell line (HeLa) Human RHOD 1:3~1:6 Negative Online Inquiry
KO26870 RHOD Knockout cell line (HCT 116) Human RHOD 1:2~1:4 Negative Online Inquiry
KO26871 RHOD Knockout cell line (A549) Human RHOD 1:3~1:4 Negative Online Inquiry

Background

RHOD Gene Knockout Cell Lines are genetically engineered cell lines in which the RHOD gene has been inactivated, allowing for the study of its biological functions and regulatory pathways. These knockout models serve as invaluable tools for researchers investigating the roles of RHOD in cellular processes, such as cytoskeletal organization, cell migration, and signal transduction. By selectively silencing the RHOD gene, these cell lines enable researchers to delineate the function of this Rho GTPase in various physiological and pathological contexts.

The precise mechanism of action for RHOD involves its role in modulating actin filament dynamics and cellular morphology through downstream effectors. By understanding the intricacies of RHOD signaling, researchers can explore its contributions to processes such as cell proliferation, adhesion, and motility, which are critical in cancer metastasis and cardiovascular health.

In research and clinical applications, RHOD Gene Knockout Cell Lines are particularly useful for drug discovery and development, as they provide a clearer understanding of how treatments may interact with this signaling pathway. Moreover, they enable the establishment of disease models that can yield insights into target validation and biomarker identification.

Compared to traditional cell lines, RHOD knockout models offer the unique advantage of specificity and accuracy in studying the gene’s function without confounding interference from normal gene expression. This specificity reduces experimental variability and enhances the reliability of experimental outcomes, making them essential for high-quality research.

For researchers and clinicians looking to deepen their understanding of cellular mechanisms and enhance their therapeutic strategies, RHOD Gene Knockout Cell Lines represent a valuable asset. They facilitate advanced research into diseases linked to Rho GTPases and contribute to the discovery of novel therapeutic approaches.

Our company is dedicated to providing high-quality biological tools, combining robust scientific expertise with a commitment to advancing research. With our expertly curated RHOD Gene Knockout Cell Lines, we empower the scientific community to uncover the intricate roles of Rho GTPases with confidence and precision.

Please note that all services are for research use only. Not intended for any clinical use.

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