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RHEBL1 Knockout Cell Lines

Gene: RHEBL1

Official Full Name: RHEB like 1provided by HGNC

Gene Summary: Enables GTP binding activity. Involved in TOR signaling and positive regulation of NF-kappaB transcription factor activity. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO29611 RHEBL1 Knockout cell line (HeLa) Human RHEBL1 1:3~1:6 Negative Online Inquiry
KO29612 RHEBL1 Knockout cell line (HCT 116) Human RHEBL1 1:2~1:4 Negative Online Inquiry
KO29613 RHEBL1 Knockout cell line (A549) Human RHEBL1 1:3~1:4 Negative Online Inquiry

Background

RHEBL1 Gene Knockout Cell Lines are genetically engineered cellular models used to study the functional role of the RHEBL1 gene, which encodes a member of the Ras superfamily of GTPases. The cell lines are meticulously designed to facilitate the investigation of cellular processes such as growth, differentiation, and signal transduction, shedding light on the pathways influenced by the RHEBL1 gene. This product harnesses the power of CRISPR-Cas9 technology, allowing for precise and stable disruption of the gene, leading to a complete knockout effect that is essential in elucidating gene function.

The primary mechanism of the RHEBL1 knockout involves inducing targeted double-strand breaks in the DNA, which are subsequently repaired by non-homologous end joining, resulting in frameshift mutations that inactivate the gene. This process not only provides researchers with tools to investigate the loss-of-function phenotypes associated with RHEBL1 but also aids in the identification of downstream signaling pathways it may influence.

Scientifically, RHEBL1 has been implicated in various cellular processes, making its study crucial for understanding tumorigenesis, cell cycle regulation, and metabolic pathways. In clinical settings, these knockout cell lines can help reveal potential therapeutic targets for diseases associated with RHEBL1 dysregulation, thereby advancing personalized medicine.

Compared to other gene knockout models, our RHEBL1 Gene Knockout Cell Lines offer high efficiency, reliability, and reproducibility due to our rigorous quality control and validation processes. These attributes enhance experimental fidelity, allowing scientists to draw more accurate conclusions from their research.

For researchers and clinicians seeking to contribute effectively to the fields of cancer biology and molecular genetics, these knockout cell lines represent an invaluable resource. Our commitment to excellence in product development stems from years of expertise in genetic engineering, ensuring that you receive high-quality products to aid your important work in advancing scientific knowledge.

Please note that all services are for research use only. Not intended for any clinical use.

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