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RHBDD1 Knockout Cell Lines

Gene: RHBDD1

Official Full Name: rhomboid domain containing 1provided by HGNC

Gene Summary: Enables serine-type endopeptidase activity. Involved in several processes, including cellular response to unfolded protein; membrane protein proteolysis; and positive regulation of protein catabolic process. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25073 RHBDD1 Knockout cell line (HeLa) Human RHBDD1 1:3~1:6 Negative Online Inquiry
KO25074 RHBDD1 Knockout cell line (HCT 116) Human RHBDD1 1:2~1:4 Negative Online Inquiry
KO25075 RHBDD1 Knockout cell line (HEK293) Human RHBDD1 1:3~1:6 Negative Online Inquiry
KO25076 RHBDD1 Knockout cell line (A549) Human RHBDD1 1:3~1:4 Negative Online Inquiry

Background

RHBDD1 Gene Knockout Cell Lines represent a powerful biological tool specifically engineered to study the functional role of the RHBDD1 gene in various cellular processes. Knockout cell lines are derived from established cellular models where specific genes have been selectively disrupted, allowing researchers to observe the effects of gene loss on cellular behavior, signaling pathways, and disease states. This precision provides a robust framework for elucidating the contributions of RHBDD1 in cellular physiology and pathology.

The primary function of RHBDD1 gene knockout cell lines lies in their ability to mimic the gene inactivation observed in certain diseases,such as cancer, neurodegeneration, and metabolic disorders. By disrupting the RHBDD1 gene, these cell lines facilitate investigations into its involvement in key mechanisms such as protein homeostasis, cellular stress responses, and endoplasmic reticulum function. Understanding these processes is crucial for identifying potential therapeutic targets and elucidating disease mechanisms at a molecular level.

The scientific importance of RHBDD1 gene knockout cell lines extends to both basic research and clinical applications. In research settings, these knockout models intersect disease biology with drug discovery efforts, enabling scientists to assess how pharmacological compounds may influence disease-relevant pathways. Clinically, these cell lines can be instrumental in developing personalized medicine approaches by understanding how variations in the RHBDD1 gene affect patient responses to treatments.

Compared to alternative models, RHBDD1 gene knockout cell lines offer unique advantages, such as validated and reproducible results in diverse experimental conditions. They provide a high-throughput platform for screening potential therapeutics and understanding multifaceted interactions within cellular networks, which are often challenging to capture with in vivo models.

Researchers and clinicians will find RHBDD1 gene knockout cell lines invaluable for their ability to deliver critical insights into gene function and regulation, thereby enabling advancements in diagnostics and targeted treatments for a variety of diseases. Our company is committed to delivering high-quality biological products backed by rigorous scientific validation and expertise, positioning us as a leader in providing essential tools for innovative research and clinical applications.

Please note that all services are for research use only. Not intended for any clinical use.

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