Gene: RGS22
Official Full Name: regulator of G protein signaling 22provided by HGNC
Gene Summary: Enables G-protein alpha-subunit binding activity. Predicted to be involved in negative regulation of signal transduction. Located in actin cytoskeleton; cytosol; and fibrillar center. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO28234 | RGS22 Knockout cell line (A549) | Human | RGS22 | 1:3~1:4 | Negative | Online Inquiry |
RGS22 Gene Knockout Cell Lines are genetically engineered cell lines characterized by the targeted disruption of the RGS22 gene, which encodes a member of the regulator of G-protein signaling family. By knocking out this gene, these cell lines allow researchers to investigate the role of RGS22 in various cellular processes, particularly in G-protein coupled receptor signaling pathways. This mechanism is pivotal in understanding how cells respond to external stimuli and regulate critical physiological functions.
The primary function of RGS22 is to accelerate the GTPase activity of G-proteins, effectively deactivating them and thereby terminating signaling events. By utilizing RGS22 knockout cell lines, researchers can elucidate the functional consequences of RGS22 loss. This can lead to insights into various disease states, including cancer, cardiovascular diseases, and neurological disorders, where altered G-protein signaling is often implicated.
Scientifically, the ability to manipulate RGS22 gene expression opens avenues for both basic research and potential therapeutic applications. In research settings, these knockout cell lines facilitate the exploration of cell signaling dynamics, drug development, and the identification of new therapeutic targets. Clinically, understanding RGS22 function could contribute to novel treatments aimed at restoring or modifying signaling pathways in diseases characterized by aberrant G-protein signaling.
What sets RGS22 Gene Knockout Cell Lines apart from alternatives is their precise genetic modification, validated performance in key assays, and the support from our dedicated technical team, which ensures that users can effectively leverage these tools in their research. Our product offers the unique advantage of enhancing reproducibility and reliability in experimental outcomes, making it an invaluable asset for researchers seeking to push the boundaries of cellular biology.
With years of expertise in genetic engineering and a commitment to providing high-quality biological products, our company ensures that researchers and clinicians have access to cutting-edge tools that can significantly accelerate scientific discovery and innovation.
Please note that all services are for research use only. Not intended for any clinical use.
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