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RCOR2 Knockout Cell Lines

Gene: RCOR2

Official Full Name: REST corepressor 2provided by HGNC

Gene Summary: Predicted to enable transcription corepressor activity. Predicted to be involved in negative regulation of DNA-templated transcription and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of histone deacetylase complex and transcription regulator complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14636 RCOR2 Knockout cell line (HeLa) Human RCOR2 1:3~1:6 Negative Online Inquiry
KO14637 RCOR2 Knockout cell line (HCT 116) Human RCOR2 1:2~1:4 Negative Online Inquiry
KO14638 RCOR2 Knockout cell line (HEK293) Human RCOR2 1:3~1:6 Negative Online Inquiry

Background

RCOR2 Gene Knockout Cell Lines are genetically modified cell lines engineered to specifically disrupt the RCOR2 gene, a key regulator linked to various biological processes, including cellular differentiation and development. By utilizing CRISPR/Cas9 technology, these cell lines enable researchers to conduct in-depth functional studies and assess the role of RCOR2 in cellular signaling pathways and gene expression regulation.

The primary function of RCOR2 Gene Knockout Cell Lines is to serve as a versatile platform for studying the consequences of gene knockout in both in vitro and in vivo environments. The absence of RCOR2 allows scientists to analyze changes in cellular behavior, including alterations in proliferation, apoptosis, and metabolic pathways. This knockout model can be particularly instrumental in elucidating the molecular mechanisms underlying diseases such as cancer, neurodegenerative disorders, and metabolic syndromes.

The scientific importance of these cell lines extends to their widespread applications in basic research, drug discovery, and translational medicine. By providing a clear genetic background devoid of RCOR2, these cell lines can facilitate a more straightforward interpretation of experimental data, enhancing the reproducibility of findings across laboratories. Furthermore, the RCOR2 knockout model allows for the identification of potential therapeutic targets by assessing the impacts of reintroducing or silencing associated signaling molecules.

When compared to alternative models, RCOR2 Gene Knockout Cell Lines offer unique advantages, including precise and efficient gene editing, high stability in various culture conditions, and compatibility with a plethora of downstream applications, such as protein assays, gene expression analysis, and pathway investigations. Additionally, these cell lines are obtainable in different backgrounds, allowing researchers to tailor their use to specific experimental needs.

For researchers and clinicians seeking to unravel the complexities of gene function and its implications in health and disease, RCOR2 Gene Knockout Cell Lines represent an invaluable resource. By facilitating the dissection of intricate biological pathways, they empower scientists to drive innovations in therapeutic strategies and biomarker discovery.

Our company is committed to advancing research through high-quality biological products, backed by extensive expertise in genetic engineering and molecular biology. We ensure that our products meet rigorous quality standards to support the scientific community in its quest for impactful discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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