Gene: RCAN3
Official Full Name: RCAN family member 3provided by HGNC
Gene Summary: Enables phosphatase binding activity and troponin I binding activity. Predicted to be involved in calcium-mediated signaling. Predicted to be located in cytosol. Predicted to be active in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO31189 | RCAN3 Knockout cell line (HeLa) | Human | RCAN3 | 1:3~1:6 | Negative | Online Inquiry |
KO31190 | RCAN3 Knockout cell line (HCT 116) | Human | RCAN3 | 1:2~1:4 | Negative | Online Inquiry |
KO31191 | RCAN3 Knockout cell line (HEK293) | Human | RCAN3 | 1:3~1:6 | Negative | Online Inquiry |
KO31192 | RCAN3 Knockout cell line (A549) | Human | RCAN3 | 1:3~1:4 | Negative | Online Inquiry |
RCAN3 Gene Knockout Cell Lines are highly specialized cellular models designed for the investigation of the regulatory effects associated with the RCAN3 gene, which encodes a member of the regulator of calcineurin (RCAN) family. These cell lines are engineered through precise gene editing techniques, enabling researchers to effectively study the physiological and pathophysiological roles of RCAN3 in various biological processes, including calcium signaling, cellular stress responses, and tissue homeostasis.
The primary function of RCAN3 involves the inhibition of calcineurin, a vital phosphatase that regulates signaling pathways initiated by calcium influx. By providing a complete knockout of this gene, the cell lines facilitate the assessment of calcineurin-dependent pathways, enabling scientists to examine how dysregulation might contribute to diseases such as heart hypertrophy, neurodegeneration, and inflammation. Furthermore, the utilization of these cell lines can unveil insights into potential therapeutic targets, fostering the development of molecules aimed at modulating these critical signaling pathways.
The scientific importance of RCAN3 Gene Knockout Cell Lines extends to both basic research and clinical applications. In research settings, they serve as indispensable tools for elucidating the molecular mechanisms underlying various disorders. Clinically, understanding the role of RCAN3 may lead to novel interventions aimed at ameliorating diseases linked to calcium signaling dysregulation.
What sets our RCAN3 Gene Knockout Cell Lines apart from alternatives is their unparalleled specificity and reliability. Engineered using advanced CRISPR/Cas9 technology, these cell lines exhibit a complete loss of RCAN3 expression, ensuring that any observed effects are directly attributable to the gene's absence. They are thoroughly characterized and validated, providing researchers with confidence in their experimental outcomes.
For researchers and clinicians alike, the value of our RCAN3 Gene Knockout Cell Lines lies in their ability to illuminate complex biological pathways and provide new avenues for therapeutic development. By integrating these models into your research, you will be equipped to contribute significantly to the understanding of calcium signaling and its implications in human health.
Our company prides itself on its commitment to advancing scientific knowledge through high-quality biological products. With expertise in genetic engineering and a deep understanding of cellular biology, we offer comprehensive solutions tailored to meet the needs of the global research community.
Please note that all services are for research use only. Not intended for any clinical use.
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