Gene: RBM23
Official Full Name: RNA binding motif protein 23provided by HGNC
Gene Summary: This gene encodes a member of the U2AF-like family of RNA binding proteins. This protein interacts with some steroid nuclear receptors, localizes to the promoter of a steroid- responsive gene, and increases transcription of steroid-responsive transcriptional reporters in a hormone-dependent manner. It is also implicated in the steroid receptor-dependent regulation of alternative splicing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO14670 | RBM23 Knockout cell line (HeLa) | Human | RBM23 | 1:3~1:6 | Negative | Online Inquiry |
KO14671 | RBM23 Knockout cell line (HCT 116) | Human | RBM23 | 1:2~1:4 | Negative | Online Inquiry |
KO14672 | RBM23 Knockout cell line (HEK293) | Human | RBM23 | 1:3~1:6 | Negative | Online Inquiry |
KO14673 | RBM23 Knockout cell line (A549) | Human | RBM23 | 1:3~1:4 | Negative | Online Inquiry |
RBM23 Gene Knockout Cell Lines are genetically engineered cell models designed specifically to study the functional roles of the RBM23 gene, which encodes RNA-binding motifs crucial for various cellular processes, including RNA splicing, stability, and transport. By providing a system in which the RBM23 gene is inactivated, these knockout cell lines enable researchers to investigate the implications of RBM23 deficiency on cellular physiology and pathophysiology.
The key mechanism by which RBM23 Gene Knockout Cell Lines function centers on the loss of RBM23, allowing for the observation of downstream effects on gene expression and cellular behavior. Researchers can assess changes in cellular dynamics, differentiate pathways, and analyze the resultant phenotypes, such as altered proliferation, apoptosis, and response to stressors. This unique capability is particularly relevant in understanding diseases where RNA regulation plays a pivotal role, including various cancers and neurological disorders.
The scientific importance of RBM23 Gene Knockout Cell Lines is immense, facilitating applications in basic research, drug discovery, and therapeutic development. Their usage provides insights into the molecular mechanisms underpinning gene regulation and cellular dysfunction, making them invaluable tools for both academic and pharmaceutical research settings.
Compared to other available cell lines, RBM23 Gene Knockout Cell Lines present distinct advantages such as precise gene editing via CRISPR/Cas9 technology, validated genetic background, and optimized culture conditions that ensure reproducibility and reliability in experimental outcomes. This specificity enhances the accuracy of experimental results, setting these cell lines apart in the realm of genetic study.
For researchers and clinicians alike, the value of RBM23 Gene Knockout Cell Lines lies in their ability to unravel complex biological processes and contribute to groundbreaking discoveries. Their application in therapeutic contexts can lead to significant advancements in the development of targeted treatments aimed at manipulating RNA pathways.
Our company, with a strong foundation in genetic engineering and cell line development, is dedicated to providing high-quality, reliable biological products tailored to the intricate needs of the scientific community. With RBM23 Gene Knockout Cell Lines, we empower researchers to drive innovation and advancement in molecular biology and therapeutic applications.
Please note that all services are for research use only. Not intended for any clinical use.
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