Gene: RAP1GAP2
Official Full Name: RAP1 GTPase activating protein 2provided by HGNC
Gene Summary: This gene encodes a GTPase-activating protein that activates the small guanine-nucleotide-binding protein Rap1 in platelets. The protein interacts with synaptotagmin-like protein 1 and Rab27 and regulates secretion of dense granules from platelets at sites of endothelial damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO29857 | RAP1GAP2 Knockout cell line (HeLa) | Human | RAP1GAP2 | 1:3~1:6 | Negative | Online Inquiry |
KO29858 | RAP1GAP2 Knockout cell line (HCT 116) | Human | RAP1GAP2 | 1:2~1:4 | Negative | Online Inquiry |
KO29859 | RAP1GAP2 Knockout cell line (HEK293) | Human | RAP1GAP2 | 1:3~1:6 | Negative | Online Inquiry |
KO29860 | RAP1GAP2 Knockout cell line (A549) | Human | RAP1GAP2 | 1:3~1:4 | Negative | Online Inquiry |
RAP1GAP2 Gene Knockout Cell Lines are essential tools designed for advanced genetic research, created to facilitate the study of the RAP1GAP2 gene's role in cellular processes. These cell lines are engineered to have the RAP1GAP2 gene inactivated, allowing researchers to analyze the downstream effects of its absence on various biological pathways, particularly those involved in cell signaling, proliferation, and differentiation.
The key function of the RAP1GAP2 gene is to encode a GTPase-activating protein that regulates the activity of RAP1, a member of the Ras superfamily of proteins. By knocking out this gene, researchers can investigate how altered RAP1 signaling influences cellular behavior and its implications in diseases, including cancer and cardiovascular disorders. The knockout model offers a distinct advantage for elucidating the mechanisms by which cellular signaling is controlled and how its dysregulation can lead to pathophysiological conditions.
The scientific importance of RAP1GAP2 Gene Knockout Cell Lines extends beyond basic research; they are invaluable in drug discovery and biotherapeutic development. Understanding the role of RAP1GAP2 in various signaling pathways enables scientists to identify potential targets for therapeutic intervention and to validate new compounds aimed at correcting dysregulated signaling.
What differentiates our RAP1GAP2 Gene Knockout Cell Lines from alternative products on the market is their rigorously validated performance and consistency. Each cell line is thoroughly characterized to ensure stable genetic modification and reproducibility across experiments, which is critical for obtaining reliable and interpretable results.
For researchers and clinicians, investing in our RAP1GAP2 Gene Knockout Cell Lines means gaining access to a powerful resource for cutting-edge studies that can lead to breakthroughs in understanding cellular mechanisms and disease states. Our commitment to high-quality biological products stems from our extensive experience and expertise in cell line development and genetic engineering, ensuring that you receive reliable products tailored to the demands of modern research.
Please note that all services are for research use only. Not intended for any clinical use.
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