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RALGPS2 Knockout Cell Lines

Gene: RALGPS2

Official Full Name: Ral GEF with PH domain and SH3 binding motif 2provided by HGNC

Gene Summary: Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in Ras protein signal transduction. Predicted to be located in cytoplasm. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14721 RALGPS2 Knockout cell line (HeLa) Human RALGPS2 1:3~1:6 Negative Online Inquiry
KO14722 RALGPS2 Knockout cell line (HCT 116) Human RALGPS2 1:2~1:4 Negative Online Inquiry
KO14723 RALGPS2 Knockout cell line (HEK293) Human RALGPS2 1:3~1:6 Negative Online Inquiry
KO14724 RALGPS2 Knockout cell line (A549) Human RALGPS2 1:3~1:4 Negative Online Inquiry

Background

RALGPS2 Gene Knockout Cell Lines represent a sophisticated tool for researchers investigating the roles of the RALGPS2 gene in cellular processes. RALGPS2, known for its involvement in Ral guanosine triphosphatase signaling pathways, is integral to various cellular functions, including cell proliferation, differentiation, and oncogenesis. These knockout cell lines have been meticulously engineered to disrupt the expression of the RALGPS2 gene, thereby allowing researchers to study the gene's specific influence on cellular behavior and signaling pathways.

The primary function of the RALGPS2 gene knockout is to provide a controlled environment in which the absence of RALGPS2 can be observed. This is achieved through the implementation of CRISPR/Cas9 technology or RNA interference methods that effectively eliminate or silence the gene. By utilizing these models, scientists can delineate the biochemical pathways influenced by RALGPS2 and assess the resultant phenotypic changes in the cells. The insights gained can lead to advancements in understanding cancer biology, neurodegenerative diseases, and other conditions linked to altered RALGPS2 activity.

Scientifically, RALGPS2 knockout cell lines hold significant importance in both basic and applied research. They can be utilized in pharmacological studies to evaluate potential therapeutic targets and drug responses, facilitating the development of novel treatment strategies. Moreover, these cell lines serve as invaluable assets in studies focusing on gene function and regulation, enhancing our understanding of complex biological systems.

What sets RALGPS2 gene knockout cell lines apart from alternative products is their high specificity and reproducibility, along with comprehensive validation protocols that ensure robust performance. Unlike transient knockdown strategies, these stable knockout lines provide a reliable resource for long-term studies, offering consistent experimental conditions that enhance data integrity.

For researchers and clinicians engaged in molecular biology, oncology, or genetics, the RALGPS2 gene knockout cell lines offer a unique solution characterized by precision and efficacy. Their ability to elucidate gene function presents significant opportunities for discovering underlying mechanisms of disease and developing targeted therapies.

Backed by our company’s commitment to excellence in biological products, we possess the expertise and resources to deliver high-quality knockout cell lines that meet the rigorous standards of the scientific community, ensuring that your research is both impactful and results-driven.

Please note that all services are for research use only. Not intended for any clinical use.

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