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RALGAPA2 Knockout Cell Lines

Gene: RALGAPA2

Official Full Name: Ral GTPase activating protein catalytic subunit alpha 2provided by HGNC

Gene Summary: Predicted to enable GTPase activator activity and protein heterodimerization activity. Predicted to be involved in activation of GTPase activity. Predicted to act upstream of or within Ral protein signal transduction; regulation of exocyst localization; and regulation of protein localization. Located in cytosol and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO08932 RALGAPA2 Knockout cell line (HeLa) Human RALGAPA2 1:3~1:6 Negative Online Inquiry
KO08933 RALGAPA2 Knockout cell line (HCT 116) Human RALGAPA2 1:2~1:4 Negative Online Inquiry
KO08934 RALGAPA2 Knockout cell line (HEK293) Human RALGAPA2 1:3~1:6 Negative Online Inquiry
KO08935 RALGAPA2 Knockout cell line (A549) Human RALGAPA2 1:3~1:4 Negative Online Inquiry

Background

RALGAPA2 Gene Knockout Cell Lines represent a revolutionary tool in genetic research, specifically designed to study the function of the RALGAPA2 gene, which is implicated in various cellular signaling pathways and disease states. These cell lines have been meticulously engineered using CRISPR/Cas9 technology to achieve precise gene disruption, allowing scientists to investigate the effects of RALGAPA2 loss-of-function in a controlled environment.

The primary function of these knockout cell lines is to facilitate the analysis of the biological processes regulated by RALGAPA2, including its role in cell proliferation, differentiation, and potentially its involvement in oncogenesis. By providing a genetic model wherein the RALGAPA2 gene is inactivated, researchers can explore downstream signaling cascades and identify novel therapeutic targets. Mechanistically, studies using these cell lines can also elucidate compensatory pathways that might be activated in response to RALGAPA2 deficiency, providing insights into cellular adaptability and resilience.

The scientific importance of RALGAPA2 Gene Knockout Cell Lines cannot be overstated; they serve as an invaluable resource in both basic and translational research. Their applications extend into understanding complex diseases, drug resistance, and developing targeted therapies in oncology and other fields. Compared to traditional methods of gene manipulation, these knockout lines provide a higher degree of specificity and reproducibility, enabling researchers to generate reliable data that can accelerate the discovery of new therapeutic strategies.

Unique selling points of RALGAPA2 Gene Knockout Cell Lines include their easy integration into existing research workflows and the robustness of the cell lines in various assays. They come with extensive characterization data to ensure consistency and reliability in experimental outcomes, giving researchers confidence in their findings. This product allows users to obtain significant insights into the biology of RALGAPA2 that other methodologies may not easily uncover.

Our company prides itself on its commitment to advancing scientific research by offering high-quality biological products, underpinned by rigorous validation processes and expert technical support. The RALGAPA2 Gene Knockout Cell Lines epitomize our dedication to providing tools that empower researchers and clinicians to unravel complex biological questions and facilitate the advancement of human health.

Please note that all services are for research use only. Not intended for any clinical use.

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