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RAET1G Knockout Cell Lines

Gene: RAET1G

Official Full Name: retinoic acid early transcript 1Gprovided by HGNC

Gene Summary: This gene encodes a member of the major histocompatibility complex (MHC) class I family of proteins. Although the encoded protein includes C-terminal transmembrane and cytoplasmic domains, proteolytic processing results in the removal of these domains and subsequent tethering to the plasma membrane by a glycosylphosphatidylinositol (GPI)-anchor. The encoded protein is one of several related ligands of the natural killer group 2, member D (NKG2D) receptor, which functions as an activating receptor in innate and adaptive immunity. This gene is present in a gene cluster on chromosome 6. [provided by RefSeq, Jul 2015]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO09665 RAET1G Knockout cell line (HeLa) Human RAET1G 1:3~1:6 Negative Online Inquiry
KO09666 RAET1G Knockout cell line (HEK293) Human RAET1G 1:3~1:6 Negative Online Inquiry
KO09667 RAET1G Knockout cell line (A549) Human RAET1G 1:3~1:4 Negative Online Inquiry

Background

RAET1G Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to study the function of the RAET1G gene, which is implicated in immune regulation and cellular responses to stress. This product represents a vital tool in the field of molecular biology, enabling researchers to elucidate the roles of RAET1G in various biological processes and diseases, particularly in cancer immunology and autoimmune disorders.

The key function of RAET1G Gene Knockout Cell Lines lies in their ability to facilitate the investigation of the gene's loss-of-function effects. By utilizing CRISPR-Cas9 gene editing technology, these cell lines are constructed to express targeted deletions of the RAET1G gene, allowing scientists to assess changes in cell proliferation, apoptosis, and immune evasion mechanisms in vitro. This investigational capability provides critical insights into how RAET1G contributes to the modulation of immune responses and cellular homeostasis.

From a scientific perspective, these knockout cell lines serve as a powerful platform in both basic research and therapeutic development. They enable the identification of potential biomarkers and novel therapeutic targets, which can be crucial for devising innovative strategies against diseases where RAET1G plays a pivotal role. In clinical settings, these models help simulate human disease conditions, allowing for a better understanding of the gene's impact on patient outcomes and treatment responses.

What sets RAET1G Gene Knockout Cell Lines apart from other similar products is their high specificity, reliability, and the streamlined process for validation of gene function. Unlike traditional methods that often struggle with off-target effects, our advanced gene-editing techniques ensure precise modifications, resulting in consistent and reproducible data. This reliability fosters greater confidence in experimental outcomes, making it an invaluable resource for researchers focused on high-stakes projects.

In an era where genetic research is rapidly evolving, the RAET1G Gene Knockout Cell Lines offer transformative potential for discovering novel therapeutic avenues and enhancing our understanding of immune regulation. Our company prides itself on our intricate expertise in genetic engineering and cell line development, providing high-quality products that meet the rigorous demands of contemporary scientific research. These knockout cell lines represent not just a product, but a commitment to supporting the advancement of scientific knowledge and innovation in the biological sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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