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RAB22A Knockout Cell Lines

Gene: RAB22A

Official Full Name: RAB22A, member RAS oncogene familyprovided by HGNC

Gene Summary: The protein encoded by this gene is a member of the RAB family of small GTPases. The GTP-bound form of the encoded protein has been shown to interact with early-endosomal antigen 1, and may be involved in the trafficking of and interaction between endosomal compartments. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO04304 RAB22A Knockout cell line (HeLa) Human RAB22A 1:3~1:6 Negative Online Inquiry
KO04305 RAB22A Knockout cell line (HCT 116) Human RAB22A 1:2~1:4 Negative Online Inquiry
KO04306 RAB22A Knockout cell line (HEK293) Human RAB22A 1:3~1:6 Negative Online Inquiry
KO04307 RAB22A Knockout cell line (A549) Human RAB22A 1:3~1:4 Negative Online Inquiry

Background

RAB22A Gene Knockout Cell Lines are specialized cellular models designed to facilitate in-depth studies of the RAB22A gene’s function, a member of the RAB GTPase family, which plays a critical role in intracellular membrane trafficking and signal transduction. These cell lines have been meticulously engineered using CRISPR/Cas9 gene-editing technology to create specific knockout variants that completely disrupt the expression of the RAB22A gene, offering a powerful tool for researchers to delineate the gene's biological role in cellular processes.

The primary function of these knockout cell lines is to enable the analysis of RAB22A-dependent pathways and mechanisms. By examining these lines, researchers can investigate alterations in endosomal trafficking, cellular proliferation, migration, and apoptosis that result from the loss of RAB22A expression. Such insights are vital for understanding its implications in various diseases, including cancer, neurodegenerative disorders, and metabolic syndromes.

In the scientific community, RAB22A's dysregulation has garnered attention due to its potential involvement in disease progression. Utilizing RAB22A Gene Knockout Cell Lines can therefore be pivotal in preclinical drug screening, biomarker discovery, and the exploration of novel therapeutic targets, making them invaluable in both basic research and clinical applications.

Compared to traditional cell models, these knockout cell lines offer unparalleled specificity in assessing gene function without the influence of compensatory pathways, thereby enhancing the reliability of experimental outcomes. Additionally, the precision of CRISPR technology ensures high efficiency and robustness, minimizing off-target effects that commonly plague other gene-editing methods.

For researchers and clinicians focused on the intersection of gene function and disease, RAB22A Gene Knockout Cell Lines provide a unique opportunity to bridge the gap between basic biology and translational research. Their use can lead to groundbreaking discoveries that not only advance our understanding of disease mechanisms but also inform the development of targeted and personalized therapies.

Our company specializes in producing high-quality genetic tools designed for research purposes. With a deep commitment to scientific advancement and an expert team of specialists in molecular biology, we strive to empower the research community with innovative solutions like the RAB22A Gene Knockout Cell Lines.

Please note that all services are for research use only. Not intended for any clinical use.

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