Gene: QSOX1
Official Full Name: quiescin sulfhydryl oxidase 1provided by HGNC
Gene Summary: This gene encodes a protein that contains domains of thioredoxin and ERV1, members of two long-standing gene families. The gene expression is induced as fibroblasts begin to exit the proliferative cycle and enter quiescence, suggesting that this gene plays an important role in growth regulation. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO35821 | QSOX1 Knockout cell line (HeLa) | Human | QSOX1 | 1:3~1:6 | Negative | Online Inquiry |
KO35822 | QSOX1 Knockout cell line (HCT 116) | Human | QSOX1 | 1:2~1:4 | Negative | Online Inquiry |
KO35823 | QSOX1 Knockout cell line (HEK293) | Human | QSOX1 | 1:3~1:6 | Negative | Online Inquiry |
KO35824 | QSOX1 Knockout cell line (A549) | Human | QSOX1 | 1:3~1:4 | Negative | Online Inquiry |
QSOX1 Gene Knockout Cell Lines are a powerful research tool engineered to study the biological functions and implications of the QSOX1 gene. This gene encodes a quiescin sulfhydryl oxidase, which plays a critical role in the formation of disulfide bonds within proteins, essential for proper protein folding and function. The knockout cell lines enable researchers to explore the effects of QSOX1 deficiency on cellular processes, including redox regulation, cell proliferation, and apoptosis, thereby providing insights into various physiological and pathological conditions.
The key mechanism of the QSOX1 Gene Knockout Cell Lines lies in their ability to facilitate the evaluation of gene function by effectively disrupting the QSOX1 gene configuration. This disruption allows for the study of downstream signaling pathways influenced by QSOX1 and assists in elucidating its role in diseases such as cancer and neurodegeneration. With these cell lines, researchers can also assess the impact of altered oxidative stress levels on cellular behavior, offering a comprehensive understanding of redox biology.
The scientific importance of these knockout cell lines is underscored by their application in both preclinical and clinical research settings. They are vital for drug discovery processes, biomarker identification, and therapeutic development, particularly in areas where the oxidative state of cells is a critical factor. Additionally, these cell lines can be utilized in genetic and biochemical assays, allowing for a diverse range of experimental designs.
Unique to our offering, the QSOX1 Gene Knockout Cell Lines come with validation data and detailed characterization, ensuring reliability and reproducibility in research. This detailed profiling distinguishes our product from competitors, who may not provide the same level of quality assurance or experimental consistency.
For researchers and clinicians focused on dissecting complex biological pathways and exploring therapeutic possibilities, the QSOX1 Gene Knockout Cell Lines represent an invaluable resource. Their ability to clarify the functional dynamics of the QSOX1 gene stands to enhance understanding and foster innovation in health-related research.
At our company, we pride ourselves on our commitment to advancing scientific discovery through high-quality biological products. Our expertise in gene editing and cell line development ensures that you receive not only a product but also a partnership in your research endeavors.
Please note that all services are for research use only. Not intended for any clinical use.
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