Gene: PYCR3
Official Full Name: pyrroline-5-carboxylate reductase 3provided by HGNC
Gene Summary: This gene encodes a protein that belongs to the pyrroline-5-carboxylate reductase family of enzymes. Members of this family catalyze the final step in proline biosynthesis, converting pyrroline-5-carboxylate to proline. Glutamate and ornithine are precursors in the synthesis of proline. The protein encoded by this gene is a cytoplasmic enzyme involved in the biosynthesis of proline from ornithine. [provided by RefSeq, Aug 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO14779 | PYCR3 Knockout cell line (HeLa) | Human | PYCR3 | 1:3~1:6 | Negative | Online Inquiry |
KO14780 | PYCR3 Knockout cell line (HCT 116) | Human | PYCR3 | 1:2~1:4 | Negative | Online Inquiry |
KO14781 | PYCR3 Knockout cell line (HEK293) | Human | PYCR3 | 1:3~1:6 | Negative | Online Inquiry |
KO14782 | PYCR3 Knockout cell line (A549) | Human | PYCR3 | 1:3~1:4 | Negative | Online Inquiry |
PYCR3 Gene Knockout Cell Lines are specialized cellular models designed to study the biological functions and therapeutic implications of the pyrroline-5-carboxylate reductase 3 (PYCR3) gene. This innovative product offers a unique platform for researchers aiming to investigate the role of PYCR3 in key cellular processes such as amino acid biosynthesis, oxidative stress response, and metabolic regulation. By effectively knocking out the PYCR3 gene, these cell lines enable the elucidation of its role in metabolic disorders, cancer biology, and neurodegeneration.
The mechanism of action behind these knockout cell lines hinges on the use of advanced genetic editing techniques, such as CRISPR/Cas9, which ensure precise deletion of the PYCR3 gene. This specificity allows researchers to assess the resultant phenotypic changes, biochemical pathways, and functional consequences tied to PYCR3 absence. As a result, these cell lines serve as invaluable tools for dissecting the multifaceted impact of PYCR3 on cellular homeostasis as well as its potential involvement in disease states.
In the realm of scientific research and clinical applications, PYCR3 Gene Knockout Cell Lines stand out due to their ability to provide insights that may lead to novel therapeutic targets. Compared to alternative models, which may yield less relevance or specificity, our knockout cell lines offer robust, reproducible results that significantly enhance experimental rigor and biological relevance.
Researchers and clinicians will find tremendous value in these cell lines due to their versatility in applications ranging from basic research to drug discovery and development efforts. The understanding gained from studying PYCR3 knockout models can propel advancements in targeted therapies, especially in the context of metabolic syndromes and malignancies.
Our company prides itself on its commitment to excellence in the production and delivery of biological research products. With a strong background in genetic engineering and cell line development, we provide scientists with state-of-the-art tools essential for groundbreaking discoveries in life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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