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PWWP3B Knockout Cell Lines

Gene: PWWP3B

Official Full Name: PWWP domain containing 3Bprovided by HGNC

Gene Summary: This gene encodes a protein which contains a mutated melanoma-associated antigen 1 domain. Proteins which contain mutated antigens are expressed at high levels on certain types of cancers. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25990 PWWP3B Knockout cell line (HCT 116) Human PWWP3B 1:2~1:4 Negative Online Inquiry
KO25991 PWWP3B Knockout cell line (HEK293) Human PWWP3B 1:3~1:6 Negative Online Inquiry

Background

PWWP3B Gene Knockout Cell Lines are genetically engineered cell lines that specifically lack the PWWP3B gene, a key regulator in various cellular processes including epigenetic regulation, protein interactions, and cell cycle progression. By utilizing targeted CRISPR-Cas9 gene-editing technology, these knockout cell lines facilitate the investigation of PWWP3B's physiological and pathological roles, enabling researchers to dissect complex cellular mechanisms and identify potential therapeutic targets.

The main function of PWWP3B involves its interaction with chromatin and other transcriptional regulators, which positions it as a pivotal component influencing gene expression and cellular differentiation. Utilizing these knockout cell lines allows for the observation of resultant phenotypes related to PWWP3B loss, thereby accelerating the understanding of its contribution to diseases such as cancer and neurodegenerative disorders. Researchers can employ these models to study signaling pathways, drug responses, and possible compensatory mechanisms, ultimately providing insight into disease progression and treatment.

The scientific importance of PWWP3B Gene Knockout Cell Lines extends beyond basic research; they are crucial in preclinical studies for drug discovery and development. By providing an accurate physiological model, they enable the evaluation of novel therapeutic compounds targeting pathways associated with PWWP3B, significantly streamlining the drug development pipeline and enhancing the likelihood of successful clinical translations.

Unique selling points of these knockout cell lines include their specificity, reproducibility, and ease of use compared to alternative models such as transient knockdown approaches or less well-characterized animal models. These features ensure that researchers can achieve consistent and reliable results, leading to more robust data and applicable outcomes.

For researchers and clinicians, the value of PWWP3B Gene Knockout Cell Lines lies in their ability to unlock new avenues in disease research, ultimately contributing to improved patient outcomes through targeted therapies. Our company prides itself on delivering high-quality biological products, backed by rigorous scientific validation and unparalleled customer support, ensuring that your research endeavors are met with confidence and expertise.

Please note that all services are for research use only. Not intended for any clinical use.

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