Gene: PTK7
Official Full Name: protein tyrosine kinase 7 (inactive)provided by HGNC
Gene Summary: This gene encodes a member of the receptor protein tyrosine kinase family of proteins that transduce extracellular signals across the cell membrane. The encoded protein lacks detectable catalytic tyrosine kinase activity, is involved in the Wnt signaling pathway and plays a role in multiple cellular processes including polarity and adhesion. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO01393 | PTK7 Knockout cell line (HeLa) | Human | PTK7 | 1:3~1:6 | Negative | Online Inquiry |
KO09959 | PTK7 Knockout cell line (HCT 116) | Human | PTK7 | 1:2~1:4 | Negative | Online Inquiry |
KO09960 | PTK7 Knockout cell line (HEK293) | Human | PTK7 | 1:3~1:6 | Negative | Online Inquiry |
KO09961 | PTK7 Knockout cell line (A549) | Human | PTK7 | 1:3~1:4 | Negative | Online Inquiry |
PTK7 Gene Knockout Cell Lines are meticulously crafted cellular models in which the PTK7 gene has been selectively disrupted, enabling researchers to study the gene's function and the biological pathways it influences. PTK7, or Protein Tyrosine Kinase 7, is crucial in various cellular processes, including cell signaling, migration, and differentiation. By knocking out this gene, researchers can investigate its roles in oncogenesis, neurodevelopment, and other pathophysiological conditions.
The primary mechanism behind PTK7 Gene Knockout Cell Lines involves CRISPR-Cas9 technology, which allows the precise editing of the genome to create cell lines devoid of functional PTK7. This innovation enables scientists to unravel the specifics of PTK7’s signaling pathways and its interactions with other molecules, providing insights critical for understanding cancer biology and neuroscience.
The scientific importance of these cell lines is underscored by their applications in both research and clinical settings. They serve as invaluable tools for drug discovery, enabling the identification of potential therapeutic targets and the screening of drug responses in a controlled environment. By studying these knockout cell lines, researchers can also simulate disease states, enhancing translational research and the development of targeted therapies.
What sets our PTK7 Gene Knockout Cell Lines apart from other models is their high specificity and reproducibility. Each line is validated for PTK7 disruption at both the mRNA and protein levels, ensuring reliable experimental outcomes. Additionally, these cell lines are available in various backgrounds, offering flexibility for diverse experimental needs.
For researchers and clinicians alike, PTK7 Gene Knockout Cell Lines represent a pivotal resource that not only accelerates the understanding of disease mechanisms but also facilitates the development of novel therapeutics. Our company prides itself on its extensive expertise in creating high-quality biological products tailored to advance the frontiers of biomedical research, ensuring our solutions meet the rigorous demands of today’s scientific community.
Please note that all services are for research use only. Not intended for any clinical use.
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