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PTGFRN Knockout Cell Lines

Gene: PTGFRN

Official Full Name: prostaglandin F2 receptor inhibitorprovided by HGNC

Gene Summary: Predicted to be involved in myoblast fusion involved in skeletal muscle regeneration. Predicted to act upstream of or within lipid droplet organization. Located in cell surface. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO03466 PTGFRN Knockout cell line (HeLa) Human PTGFRN 1:3~1:6 Negative Online Inquiry
KO03467 PTGFRN Knockout cell line (HCT 116) Human PTGFRN 1:2~1:4 Negative Online Inquiry
KO03468 PTGFRN Knockout cell line (HEK293) Human PTGFRN 1:3~1:6 Negative Online Inquiry
KO03469 PTGFRN Knockout cell line (A549) Human PTGFRN 1:3~1:4 Negative Online Inquiry

Background

PTGFRN Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to lack the expression of the Prostaglandin F2 alpha Receptor Negative (PTGFRN) gene. This product allows researchers to study the functional implications of PTGFRN absence in various biological processes, particularly those related to inflammatory responses and reproductive biology. Through CRISPR/Cas9 gene-editing technology, these cell lines are established, ensuring precise deletions of the target gene while maintaining the integrity of the remaining genetic material.

The primary function of PTGFRN Gene Knockout Cell Lines lies in their utility as an experimental model to elucidate the roles of PTGFRN in cell signaling pathways, particularly those influenced by prostaglandins. By examining the cellular behavior in the absence of PTGFRN, researchers can investigate its contributions to processes such as cell proliferation, apoptosis, and immune responses, thus facilitating a deeper understanding of its physiological and pathological roles.

The scientific importance of these knockout cell lines is evident in both research and clinical settings. They serve as essential tools for drug discovery, allowing for the identification of potential therapeutic targets for diseases where PTGFRN is implicated, such as certain cancers or inflammatory conditions. Additionally, they provide a platform for testing novel treatments or gene therapies aimed at modifying cellular pathways affected by PTGFRN.

What sets PTGFRN Gene Knockout Cell Lines apart from traditional cell models is their precise genetic modification and the reliability of data obtained from their use. Unlike transient knockdown methods, which often produce inconsistent results, these stable cell lines offer reproducibility and long-term viability for extended experiments. This reliability makes them invaluable to both academic researchers and biopharmaceutical companies seeking robust data for their innovations.

For researchers, clinicians, and biopharmaceutical professionals, PTGFRN Gene Knockout Cell Lines present a unique opportunity to explore uncharted territories in cellular biology. The insights gained from using these advanced models can pave the way for groundbreaking discoveries and potential new therapies. Our company prides itself on its expertise in producing high-quality genetic tools that empower researchers, facilitating novel discoveries and advancements in genetic research and therapeutic developments.

Please note that all services are for research use only. Not intended for any clinical use.

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