Gene: PSIP1
Official Full Name: PC4 and SRSF1 interacting protein 1provided by HGNC
Gene Summary: Enables DNA-binding transcription factor binding activity; chromatin binding activity; and transcription coactivator activity. Involved in mRNA 5'-splice site recognition and positive regulation of transcription by RNA polymerase II. Located in heterochromatin; nuclear periphery; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO31133 | PSIP1 Knockout cell line (HeLa) | Human | PSIP1 | 1:3~1:6 | Negative | Online Inquiry |
KO31134 | PSIP1 Knockout cell line (HCT 116) | Human | PSIP1 | 1:2~1:4 | Negative | Online Inquiry |
KO31135 | PSIP1 Knockout cell line (HEK293) | Human | PSIP1 | 1:3~1:6 | Negative | Online Inquiry |
KO31136 | PSIP1 Knockout cell line (A549) | Human | PSIP1 | 1:3~1:4 | Negative | Online Inquiry |
PSIP1 Gene Knockout Cell Lines are genetically engineered cellular models specifically designed to facilitate the study of the PSIP1 (PC4 and SFRS1 Interaction Protein 1) gene's role in cellular processes. By utilizing the CRISPR-Cas9 gene-editing technology, these cell lines have been meticulously developed to provide a complete knockout of the PSIP1 gene, ensuring that researchers have a reliable tool for investigating the repercussions of PSIP1 loss on cellular functions, gene regulation, and disease mechanisms.
The primary function of PSIP1 involves its participation in the transcriptional regulation of various genes and its integral role in DNA repair pathways. By employing the PSIP1 Gene Knockout Cell Lines, scientists can elucidate the gene's contributions to critical processes, such as cell cycle regulation, apoptosis, and response to stress. Such insights are invaluable for advancing our understanding of cancer biology, where abnormal PSIP1 expression may be implicated.
The scientific importance of these knockout cell lines extends to multiple research applications, including drug discovery and development, gene therapy exploration, and basic biological research. Their use can dramatically accelerate hypothesis testing, allowing researchers to examine the effects of potential therapeutics on cells lacking PSIP1 function, thereby streamlining the pathway to insights in treatment approaches.
Unlike conventional knockout methods, the precision of the CRISPR-Cas9 technology provides a clean knockout without causing off-target mutations, thus enhancing the reliability of experimental outcomes. Furthermore, the PSIP1 Gene Knockout Cell Lines are compatible with various assays, including high-throughput screening, making them accessible and user-friendly for many research laboratories.
For researchers and clinicians looking to deepen their understanding of gene functions and associated pathways, the PSIP1 Gene Knockout Cell Lines represent a unique and powerful resource. Our company specializes in the development of high-quality biological products, and with a commitment to enhancing scientific research, we are confident that our cell lines will significantly contribute to your research endeavors and clinical advancements.
Please note that all services are for research use only. Not intended for any clinical use.
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