Gene: PSG1
Official Full Name: pregnancy specific beta-1-glycoprotein 1provided by HGNC
Gene Summary: The human placenta is a multihormonal endocrine organ that produces hormones, enzymes, and other molecules that support fetal survival and development. Pregnancy-specific beta-1-glycoprotein (PSBG, PSG) is a major product of the syncytiotrophoblast, reaching concentrations of 100 to 290 mg/l at term in the serum of pregnant women (Horne et al., 1976 [PubMed 971765]). PSG is a member of the immunoglobulin (Ig) superfamily (Watanabe and Chou, 1988 [PubMed 3257488]; Streydio et al., 1988 [PubMed 3260773]).[supplied by OMIM, Oct 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO35859 | PSG1 Knockout cell line (A549) | Human | PSG1 | 1:3~1:4 | Negative | Online Inquiry |
PSG1 Gene Knockout Cell Lines are advanced biological tools designed for investigating the functional role of the PSG1 gene in various cellular processes. These engineered cell lines have undergone precise gene-editing techniques to create specific knockouts, thereby allowing researchers to observe the physiological and molecular consequences of the absence of PSG1. By eliminating this gene, scientists can explore its involvement in key biological functions such as immune response modulation, trophoblast function, and metabolic processes, making these cell lines invaluable in both basic and applied research.
The operational mechanism of PSG1 Gene Knockout Cell Lines involves the use of CRISPR/Cas9 technology or similar genome-editing methodologies that accurately disrupt the PSG1 gene sequence, ensuring the complete knockout of its expression. This precision allows for reliable assessments of cellular behaviors in controlled experiments, such as gene expression analysis, pathway elucidation, and therapeutic target validation. Researchers can study the implications of PSG1 deficiency on cellular morphology, secretory functions, and response to pharmacological agents.
Scientifically, these cell lines offer significant insights into various conditions where PSG1 may play a pivotal role, including gestational complications and autoimmune diseases. Their applications span across academic research, pharmaceutical development, and clinical settings, aiding in the identification of new biomarkers and therapeutic strategies.
What sets PSG1 Gene Knockout Cell Lines apart from alternatives is their high specificity and reproducibility, which ensure that experimental results are both reliable and valid. Furthermore, these cell lines are optimized for ease of use in various in vitro assays, encompassing a wide array of applications in the life sciences, thus catering to diverse research needs.
For researchers and clinicians seeking to delve deeper into the fundamental biology of PSG1, these knockout cell lines provide a unique and robust platform to advance their studies. By utilizing PSG1 Gene Knockout Cell Lines, users are equipped with powerful tools to uncover novel insights and drive forward the frontiers of science.
Our company specializes in high-quality biological products and advanced cell line development, boasting a team of experts committed to delivering superior research tools. With our commitment to innovation and scientific excellence, we continue to support researchers worldwide in their quest for knowledge and discovery.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.