Gene: Prmt2
Official Full Name: protein arginine N-methyltransferase 2provided by MGI
Gene Summary: Enables beta-catenin binding activity; histone H3 methyltransferase activity; and protein-arginine N-methyltransferase activity. Involved in negative regulation of G1/S transition of mitotic cell cycle; regulation of DNA-templated transcription; and response to hypoxia. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human PRMT2 (protein arginine methyltransferase 2). [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO37199 | PRMT2 Knockout cell line (HeLa) | Human | PRMT2 | 1:3~1:6 | Negative | Online Inquiry |
KO37200 | PRMT2 Knockout cell line (HCT 116) | Human | PRMT2 | 1:2~1:4 | Negative | Online Inquiry |
KO37201 | PRMT2 Knockout cell line (HEK293) | Human | PRMT2 | 1:3~1:6 | Negative | Online Inquiry |
KO37202 | PRMT2 Knockout cell line (A549) | Human | PRMT2 | 1:3~1:4 | Negative | Online Inquiry |
Prmt2 Gene Knockout Cell Lines are specialized laboratory models designed to elucidate the biological roles of the protein arginine methyltransferase 2 (Prmt2) by rendering its gene inoperative. This innovative product enables researchers to study the consequences of Prmt2 absence, providing insights into its involvement in critical cellular processes such as gene expression regulation, signal transduction, and cell cycle progression.
The key function of these knockout cell lines lies in their ability to mimic certain disease states, thereby facilitating a better understanding of both normal and pathological biology. By utilizing these cell lines, researchers can easily investigate the molecular mechanisms underlying a variety of diseases, including cancer, neurological disorders, and metabolic syndromes. The targeted knockout of the Prmt2 gene effectively silences its expression, thereby allowing for the observation of resultant phenotypes—such as altered growth rates, changes in differentiation, and variations in response to external stimuli.
The significance of Prmt2 Gene Knockout Cell Lines extends beyond basic research applications; they have valuable implications in drug discovery and development. By providing a simplified model to test potential therapeutic agents, these cell lines can significantly reduce the time and cost associated with the early stages of drug development. In comparison to alternative models, such as RNA interference or overexpression systems, Prmt2 knockout cell lines offer a permanent and stable genetic alteration that more accurately reflects native cellular environments.
Researchers and clinicians can greatly benefit from this product as it not only enhances the reliability of experimental results but also fosters an environment conducive to innovative discoveries. The ability to pinpoint the biological consequences of Prmt2 loss in a controlled setting accelerates the pace of research and promotes breakthroughs in therapeutic strategies.
Our company prides itself on expertise in delivering high-quality biological products essential for advancing scientific discovery. With a commitment to supporting the research community, we ensure that our Prmt2 Gene Knockout Cell Lines are meticulously developed to meet the most stringent standards, empowering scientists to push the boundaries of knowledge in gene function and its implications in health and disease.
Please note that all services are for research use only. Not intended for any clinical use.
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