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PRDX6 Knockout Cell Lines

Gene: PRDX6

Official Full Name: peroxiredoxin 6provided by HGNC

Gene Summary: The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO09372 PRDX6 Knockout cell line (HeLa) Human PRDX6 1:3~1:6 Negative Online Inquiry
KO09373 PRDX6 Knockout cell line (HCT 116) Human PRDX6 1:2~1:4 Negative Online Inquiry
KO09374 PRDX6 Knockout cell line (HEK293) Human PRDX6 1:3~1:6 Negative Online Inquiry
KO09375 PRDX6 Knockout cell line (A549) Human PRDX6 1:3~1:4 Negative Online Inquiry

Background

PRDX6 Gene Knockout Cell Lines are advanced cellular models engineered to specifically inhibit the expression of the peroxiredoxin 6 gene (PRDX6), which plays a pivotal role in oxidative stress response and cellular signaling pathways. These knockout cell lines serve as valuable tools in understanding the biological functions of PRDX6, including its involvement in reactive oxygen species (ROS) detoxification and its implications in various diseases, such as cancer and neurodegenerative disorders.

The key mechanism by which PRDX6 Gene Knockout Cell Lines operate involves the complete deletion of the PRDX6 gene, leading to a significant alteration in the intracellular redox state. This cellular alteration allows researchers to study the phenotypic consequences of PRDX6 loss, providing insights into its role in managing oxidative stress and cellular aging. By using these models, scientists can investigate the downstream effects of PRDX6 deficiency on key metabolic and signaling pathways, thus enhancing the understanding of its contribution to various physiological and pathological processes.

The scientific importance of these knockout cell lines extends to their diverse applications in research settings, particularly in the fields of oncology and neurobiology. Researchers can utilize these models to explore therapeutic targets and evaluate the efficacy of antioxidant compounds, contributing valuable data relevant for drug development and precision medicine approaches.

One of the standout advantages of PRDX6 Gene Knockout Cell Lines is their specificity and reproducibility. Unlike alternative models that may have off-target effects or retain partial gene expression, these knockout lines guarantee complete gene deletion, ensuring that the data obtained is both reliable and informative. This specificity allows for robust experimental designs, enabling researchers to draw more accurate conclusions regarding the role of PRDX6 in disease states.

Furthermore, the versatility of these cell lines makes them suitable for a variety of experimental applications, including drug screening, gene expression analysis, and mechanistic studies. For researchers and clinicians aiming to delve into oxidative stress mechanisms, these knockout cell lines represent an invaluable resource. Their ability to facilitate breakthroughs in understanding cell death pathways and tissue damage in various diseases underscores their essential role in translational research.

At our company, we leverage extensive expertise in biotechnology and cellular models to provide high-quality research products. With a commitment to advancing molecular biology research, our PRDX6 Gene Knockout Cell Lines are designed to enhance your research capabilities and contribute to meaningful scientific discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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