Gene: PRDM10
Official Full Name: PR/SET domain 10provided by HGNC
Gene Summary: The protein encoded by this gene is a transcription factor that contains C2H2-type zinc-fingers. It also contains a positive regulatory domain, which has been found in several other zinc-finger transcription factors including those involved in B cell differentiation and tumor suppression. Studies of the mouse counterpart suggest that this protein may be involved in the development of the central nerve system (CNS), as well as in the pathogenesis of neuronal storage disease. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO14904 | PRDM10 Knockout cell line (HeLa) | Human | PRDM10 | 1:3~1:6 | Negative | Online Inquiry |
KO14905 | PRDM10 Knockout cell line (HCT 116) | Human | PRDM10 | 1:2~1:4 | Negative | Online Inquiry |
KO14906 | PRDM10 Knockout cell line (HEK293) | Human | PRDM10 | 1:3~1:6 | Negative | Online Inquiry |
PRDM10 Gene Knockout Cell Lines are genetically modified cell lines that have had the PRDM10 gene systematically disrupted or "knocked out." This process involves targeted gene editing techniques, such as CRISPR/Cas9 or homologous recombination, to create a loss-of-function mutation in the PRDM10 gene. This innovation allows researchers to study the gene’s specific roles in various biological processes, including cellular differentiation, proliferation, and response to stress, thereby elucidating the functional consequences of its absence.
The core mechanism of these cell lines lies in their ability to mimic specific genetic alterations found in disease models, particularly in cancer and neurodegenerative disorders where PRDM10 may play a critical regulatory role. By providing a model for observing the effects of gene knockout on cellular behavior, these cell lines enable the exploration of pathways related to tumorigenesis, neurodevelopment, and other pivotal biological mechanisms.
PRDM10 Gene Knockout Cell Lines hold significant importance in both research and clinical settings. They are invaluable tools for researchers investigating gene function and disease mechanisms, as they facilitate the study of genetic contributions to cellular dynamics. Moreover, they can support drug discovery efforts by enabling the assessment of therapeutic targets under conditions that better mimic the disease state.
Compared to existing models, these knockout cell lines stand out due to their precision, allowing for specific gene targeting that eliminates off-target effects commonly observed with less sophisticated techniques. Moreover, their reproducibility and ease of use make them a preferred choice for laboratories focused on high-throughput experiments and functional assays.
For researchers and clinicians, the value of PRDM10 Gene Knockout Cell Lines is evident—they offer a robust platform for the exploration of gene functions and potential interventions. By integrating these lines into their work, users can advance their understanding of PRDM10’s role in health and disease, potentially leading to new therapeutic opportunities.
Our company possesses a wealth of expertise in genetic engineering and cellular biology, ensuring that our PRDM10 Gene Knockout Cell Lines are ethically produced, thoroughly validated, and consistently reliable for the most progressive scientific inquiries.
Please note that all services are for research use only. Not intended for any clinical use.
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