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PPP4R3B Knockout Cell Lines

Gene: PPP4R3B

Official Full Name: protein phosphatase 4 regulatory subunit 3Bprovided by HGNC

Gene Summary: Predicted to enable protein phosphatase activator activity. Involved in regulation of double-strand break repair. Located in centrosome and nuclear speck. Part of chromatin and protein phosphatase 4 complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14922 PPP4R3B Knockout cell line (HeLa) Human PPP4R3B 1:3~1:6 Negative Online Inquiry
KO14923 PPP4R3B Knockout cell line (HCT 116) Human PPP4R3B 1:2~1:4 Negative Online Inquiry
KO14924 PPP4R3B Knockout cell line (HEK293) Human PPP4R3B 1:3~1:6 Negative Online Inquiry
KO14925 PPP4R3B Knockout cell line (A549) Human PPP4R3B 1:3~1:4 Negative Online Inquiry

Background

PPP4R3B Gene Knockout Cell Lines are specialized cellular models designed for the study of the PPP4R3B gene, which encodes a regulatory subunit of protein phosphatase 4. This product allows for the precise examination of the functional role of PPP4R3B in various biological processes, including cell signaling, growth regulation, and apoptosis. By utilizing gene editing techniques, these knockout cell lines have been generated to lack the expression of PPP4R3B, providing a valuable resource for researchers investigating the gene's contributions to cellular mechanisms and disease pathogenesis.

The key functions of the PPP4R3B Gene Knockout Cell Lines enable the exploration of downstream signaling pathways and regulatory networks influenced by the absence of this specific phosphatase regulatory subunit. These cell lines can help elucidate the substrate specificity and functional implications of PPP4R3B in developmental biology and cancer research, allowing for the isolation of the molecular events triggered by its inactivation.

In scientific research, the relevance of these knockout cell lines transcends basic experiments, finding essential applications in preclinical drug testing, disease modeling, and the development of gene therapies. They provide crucial insights into the role of protein phosphatases in cancer progression, thus potentially informing therapeutic strategies.

Compared to alternative cellular models, the specificity and reliability of PPP4R3B Gene Knockout Cell Lines stand out. They provide a targeted approach to studying gene function without the confounding effects of residual activity, often observed in knockdown studies. This precision enhances the reproducibility of experiments and the validity of the results, making these cell lines an indispensable tool for researchers.

For researchers and clinicians, investing in PPP4R3B Gene Knockout Cell Lines offers robust advantages. By enabling detailed investigation of gene function, these models facilitate the advancement of scientific knowledge and therapeutic discovery. The ability to perform knockout studies with confidence supports groundbreaking developments in the understanding of various diseases associated with dysfunction in phosphatase regulation.

Our company is committed to providing high-quality research tools, including the PPP4R3B Gene Knockout Cell Lines, developed through rigorous scientific methodologies. Our expertise in cellular biology and gene editing ensures that customers receive trusted products that can significantly enhance their research capabilities and outcomes.

Please note that all services are for research use only. Not intended for any clinical use.

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