Gene: PPP1R9B
Official Full Name: protein phosphatase 1 regulatory subunit 9Bprovided by HGNC
Gene Summary: This gene encodes a scaffold protein that functions as a regulatory subunit of protein phosphatase 1a. Expression of this gene is particularly high in dendritic spines, suggesting that the encoded protein may play a role in receiving signals from the central nervous system. The encoded protein has putative tumor suppressor function and decreased expression has been observed in tumors. [provided by RefSeq, Feb 2014]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO24719 | PPP1R9B Knockout cell line (HeLa) | Human | PPP1R9B | 1:3~1:6 | Negative | Online Inquiry |
KO24720 | PPP1R9B Knockout cell line (HCT 116) | Human | PPP1R9B | 1:2~1:4 | Negative | Online Inquiry |
KO24721 | PPP1R9B Knockout cell line (HEK293) | Human | PPP1R9B | 1:3~1:6 | Negative | Online Inquiry |
KO24722 | PPP1R9B Knockout cell line (A549) | Human | PPP1R9B | 1:3~1:4 | Negative | Online Inquiry |
PPP1R9B Gene Knockout Cell Lines are specialized cellular models designed to facilitate the study of the PPP1R9B gene's function by effectively disabling its expression. These cell lines are generated through cutting-edge CRISPR/Cas9 genome-editing technology, which induces targeted double-strand breaks in the gene of interest, leading to knockout mutations that prevent its normal protein synthesis. As a result, researchers can explore the biological roles and pathways influenced by PPP1R9B, including its involvement in neuronal signaling and synaptic function.
The key mechanism of these knockout cell lines is to mimic the loss-of-function scenarios in vivo, allowing scientists to dissect cellular processes that contribute to various physiological states and pathological conditions. By observing the resulting phenotypic changes, researchers can gain insights into the role of PPP1R9B in developmental biology, neurobiology, and diseases such as neurodegeneration and psychiatric disorders.
The scientific importance of PPP1R9B Gene Knockout Cell Lines lies in their application potential in both basic and translational research settings. They serve as invaluable tools for investigating gene function, screening therapeutic compounds, and validating drug targets. Moreover, these models can improve our understanding of gene-environment interactions, which are crucial in developing precision medicine approaches.
Compared to traditional methods for gene silencing, such as RNA interference, these knockout cell lines offer enhanced specificity and stability. Unlike transient knockdowns, which are often short-lived and may lead to off-target effects, gene knockout provides a permanent alteration in the genetic landscape, yielding more reliable and reproducible results.
By investing in PPP1R9B Gene Knockout Cell Lines, researchers and clinicians gain access to a powerful resource for advancing their studies, driving innovations in gene therapy, and developing novel therapeutic strategies. With our extensive experience in cell line development and gene editing technologies, our company is dedicated to providing high-quality biological products that empower the scientific community to further explore the complexities of gene regulation and expression.
Please note that all services are for research use only. Not intended for any clinical use.
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