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PPP1R9A Knockout Cell Lines

Gene: PPP1R9A

Official Full Name: protein phosphatase 1 regulatory subunit 9Aprovided by HGNC

Gene Summary: This gene is imprinted, and located in a cluster of imprinted genes on chromosome 7q12. This gene is transcribed in both neuronal and multiple embryonic tissues, and it is maternally expressed mainly in embryonic skeletal muscle tissues and biallelically expressed in other embryonic tissues. The protein encoded by this gene includes a PDZ domain and a sterile alpha motif (SAM). It is a regulatory subunit of protein phosphatase I, and controls actin cytoskeleton reorganization. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14938 PPP1R9A Knockout cell line (HeLa) Human PPP1R9A 1:3~1:6 Negative Online Inquiry
KO14939 PPP1R9A Knockout cell line (HCT 116) Human PPP1R9A 1:2~1:4 Negative Online Inquiry
KO14940 PPP1R9A Knockout cell line (HEK293) Human PPP1R9A 1:3~1:6 Negative Online Inquiry
KO14941 PPP1R9A Knockout cell line (A549) Human PPP1R9A 1:3~1:4 Negative Online Inquiry

Background

PPP1R9A Gene Knockout Cell Lines are precisely engineered cellular models that lack the expression of the PPP1R9A gene, which encodes the Protein Phosphatase 1 Regulatory Subunit 9A. By facilitating the complete absence of this gene product, these cell lines enable researchers to investigate the biological role of PPP1R9A in various cellular processes, including signal transduction, cell cycle regulation, and metabolic pathways.

The key function of these gene knockout cell lines lies in their ability to help elucidate the regulatory mechanisms by which PPP1R9A influences cellular dynamics, ultimately impacting gene expression and protein activity in an array of biological contexts. The absence of this protein phosphatase regulator can offer insights into its role in diseases such as cancer, neurodegenerative disorders, and metabolic syndromes, making these cell lines valuable tools for basic and applied research.

Scientifically, the applications for PPP1R9A Gene Knockout Cell Lines are vast, encompassing molecular biology studies, pharmacological testing, and gene therapy research. In clinical settings, understanding how the loss of PPP1R9A influences disease can lead to the identification of novel therapeutic targets and biomarker development.

One notable advantage of using our PPP1R9A Gene Knockout Cell Lines over alternatives, such as CRISPR/Cas9 modified cells, is that they offer a ready-to-use model with complete characterizations, ensuring consistency and reproducibility in experiments. This allows researchers to save valuable time and resources by providing a stable and reliable system for gene function studies.

For researchers and clinicians, the value of PPP1R9A Gene Knockout Cell Lines cannot be overstated. They serve as a critical platform to accelerate discoveries in diverse fields, leading to potential therapeutic advancements that could benefit patients suffering from complex diseases.

Leveraging years of expertise in cellular model development, our company is committed to providing high-quality biological products that support innovative research, ensuring that scientists have access to tools that expand their understanding of gene function and disease biology.

Please note that all services are for research use only. Not intended for any clinical use.

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