Gene: PPIL3
Official Full Name: peptidylprolyl isomerase like 3provided by HGNC
Gene Summary: This gene encodes a member of the cyclophilin family. Cyclophilins catalyze the cis-trans isomerization of peptidylprolyl imide bonds in oligopeptides. They have been proposed to act either as catalysts or as molecular chaperones in protein-folding events. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO21876 | PPIL3 Knockout cell line (HeLa) | Human | PPIL3 | 1:3~1:6 | Negative | Online Inquiry |
KO21877 | PPIL3 Knockout cell line (HCT 116) | Human | PPIL3 | 1:2~1:4 | Negative | Online Inquiry |
KO21878 | PPIL3 Knockout cell line (HEK293) | Human | PPIL3 | 1:3~1:6 | Negative | Online Inquiry |
KO21879 | PPIL3 Knockout cell line (A549) | Human | PPIL3 | 1:3~1:4 | Negative | Online Inquiry |
PPIL3 Gene Knockout Cell Lines are specialized cellular models created by employing CRISPR-Cas9 gene editing technology to specifically disrupt the PPIL3 gene, which encodes the peptidylprolyl isomerase-like protein 3. These cell lines serve as crucial tools for tackling the functional roles of PPIL3 in biological processes. By eliminating expression of this gene, researchers can investigate its involvement in critical cellular mechanisms such as protein folding, signal transduction, and overall cellular stress responses.
The primary function of PPIL3 gene knockout cell lines lies in their ability to elucidate the gene's contribution to various diseases, particularly those related to cellular homeostasis and stress responses. Researchers can perform functional assays to assess how disruption of the PPIL3 gene influences cell viability, proliferation, and response to environmental stressors. This model can also facilitate the study of PPIL3's role in the pathology of specific diseases, such as cancer or neurodegenerative disorders, thereby enhancing our understanding of these complex mechanisms.
The scientific importance of these knockout cell lines is underscored by their application in both research and clinical settings. In laboratories, they provide a reliable model for drug discovery and validation, particularly in identifying potential therapeutic targets. Clinically, they can be leveraged to develop new treatment strategies that target pathways involving PPIL3.
What sets our PPIL3 Gene Knockout Cell Lines apart from alternatives is their meticulous design and validation, which ensures consistent and reproducible performance. This reliability is essential for researchers seeking robust experimental outcomes. Additionally, our commitment to quality means these cell lines are produced under stringent conditions, guaranteeing high purity and viability.
For researchers and clinicians alike, the ability to manipulate the PPIL3 gene opens new avenues for exploration and discovery, making these knockout cell lines an invaluable addition to any laboratory focused on cellular and molecular biology. With extensive expertise in cell line development and gene editing technologies, our company is dedicated to providing high-quality biological products, empowering researchers to advance their studies and achieve groundbreaking results.
Please note that all services are for research use only. Not intended for any clinical use.
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