Gene: PPFIBP2
Official Full Name: PPFIA binding protein 2provided by HGNC
Gene Summary: This gene encodes a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. The encoded protein is a beta liprin and plays a role in axon guidance and neuronal synapse development by recruiting LAR protein-tyrosine phosphatases to the plasma membrane. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO34135 | PPFIBP2 Knockout cell line (HCT 116) | Human | PPFIBP2 | 1:2~1:4 | Negative | Online Inquiry |
KO34136 | PPFIBP2 Knockout cell line (HEK293) | Human | PPFIBP2 | 1:3~1:6 | Negative | Online Inquiry |
KO34137 | PPFIBP2 Knockout cell line (A549) | Human | PPFIBP2 | 1:3~1:4 | Negative | Online Inquiry |
PPFIBP2 Gene Knockout Cell Lines are genetically modified cell lines that have had the PPFIBP2 gene effectively disrupted or eliminated through advanced genome editing techniques such as CRISPR-Cas9. This targeted gene knockout facilitates in-depth investigations into the biological functions and pathways regulated by PPFIBP2, which encodes a protein integral to cell adhesion, migration, and signal transduction processes. By creating a specific model for the study of PPFIBP2’s role, researchers can examine its contributions to various cellular behaviors and disease mechanisms.
The primary function of the PPFIBP2 Gene Knockout Cell Lines is to serve as a tool for elucidating the functional ramifications of PPFIBP2 loss. Through techniques like Western blotting, immunofluorescence, and RNA sequencing, scientists can dissect its involvement in cellular processes related to cancer metastasis, wound healing, and tissue remodeling. Such insights are critical for guiding the development of therapeutic strategies targeting pathways influenced by PPFIBP2.
Significantly, these knockout cell lines are of high utility in both basic research and clinical settings where understanding pathological states is crucial. For example, they can be instrumental in cancer research focused on understanding tumor behavior and response to drugs, opening avenues for novel treatment modalities.
The PPFIBP2 Gene Knockout Cell Lines offer distinct advantages over traditional models, including higher specificity and reproducibility, which are essential for generating reliable results. Their establishment allows for a more precise understanding of gene function compared to partial inhibition methods, such as knockdown strategies that may yield incomplete or transient effects.
These cell lines are invaluable to researchers and clinicians striving to uncover the complexities of cellular interactions and disease progression linked to the PPFIBP2 gene. By leveraging our advanced gene editing capabilities and commitment to delivering precision research tools, we provide exceptional support to the scientific community, facilitating breakthroughs that enhance our understanding of molecular biology and its implications for health and disease management.
Please note that all services are for research use only. Not intended for any clinical use.
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